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Chemical Structure| 2150-44-9 Chemical Structure| 2150-44-9
Chemical Structure| 2150-44-9

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Methyl 3,5-dihydroxybenzoate is a biochemical reagent with antioxidant and anti-inflammatory properties.

4.5 *For Research Use Only !

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Product Details of Methyl 3,5-dihydroxybenzoate

CAS No. :2150-44-9
Formula : C8H8O4
M.W : 168.15
SMILES Code : COC(=O)C1=CC(O)=CC(O)=C1
MDL No. :MFCD00002289
InChI Key :RNVFYQUEEMZKLR-UHFFFAOYSA-N
Pubchem ID :75076

Safety of Methyl 3,5-dihydroxybenzoate

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of Methyl 3,5-dihydroxybenzoate

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2150-44-9 ]

[ 2150-44-9 ] Synthesis Path-Downstream   1~9

  • 2
  • [ 2150-36-9 ]
  • [ 2150-44-9 ]
  • 3
  • [ 2150-36-9 ]
  • [ 2150-44-9 ]
  • [ 114223-14-2 ]
  • 4
  • [ 2150-44-9 ]
  • [ 151229-84-4 ]
  • [ 901758-90-5 ]
  • 7
  • [ 40915-37-5 ]
  • [ 2150-44-9 ]
  • C20H24O6 [ No CAS ]
  • 8
  • [ 2150-44-9 ]
  • [ 1196155-38-0 ]
  • methyl 3-((4-cyano-6-(trifluoromethyl)pyridin-2-yl)oxy)-5-hydroxybenzoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
34% With potassium carbonate; In N,N-dimethyl-formamide; at 20℃; for 16h; To a stirred solution of methyl 3,5-dihydroxybenzoate 2 (163 mg, 0.97 mmol) in DMF (10 mL) at RT, were added K2C03 (161 mg, 1.16 mmol) and 2-chloro-6- (trifluoromethyl)isonicotinonitrile 1 (200 mg, 0.97 mmol). The reaction mixture was stirred at RT for 16 h. The mixture was quenched with water (20 mL) and extracted with EtOAc (2 x 20 mL), and the combined organic extracts were washed with brine (10 mL), dried (Na2S04), filtered and concentrated. The residue was purified (silica gel; eluting 20-25percent EtOAc/hexanes) to afford compound 3 (110 mg, 34percent) as a white solid. 1H NMR (500MHz, CDC13): delta 7.59 (s, 1H), 7.41 - 7.44 (m, 2H), 7.36 (s, 1H), 6.90 (br s, 1H), 3.91 (s, 3H); LCMS Mass: 339.1 (M++l).
  • 9
  • [ 2150-44-9 ]
  • [ 162709-84-4 ]
  • C51H86O7 [ No CAS ]
 

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