Home Cart Sign in  
Chemical Structure| 1119-62-6 Chemical Structure| 1119-62-6
Chemical Structure| 1119-62-6

Dithiodipropionic acid

CAS No.: 1119-62-6

Dithiodipropionic acid can form nanostructures (CPUL1-DA NAs) with CPUL1 (a TrxR inhibitor), which are more effective than free CPUL1 in generating reactive oxygen species (ROS), inducing apoptosis, and enhancing the antitumor effect on HUH7 cancer cells.

4.5 *For Research Use Only !

Cat. No.: A161411 Purity: 98%

Change View

Size Price

US Stock

Global Stock

In Stock
25g łÇͶÊÊ Inquiry Inquiry
100g ł§Ç¶ÊÊ Inquiry Inquiry
250g łÿͶÊÊ Inquiry Inquiry

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • 25g

    łÇͶÊÊ

  • 100g

    ł§Ç¶ÊÊ

  • 250g

    łÿͶÊÊ

In Stock

- +

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of Dithiodipropionic acid

CAS No. :1119-62-6
Formula : C6H10O4S2
M.W : 210.27
SMILES Code : O=C(O)CCSSCCC(O)=O
MDL No. :MFCD00002780
InChI Key :YCLSOMLVSHPPFV-UHFFFAOYSA-N
Pubchem ID :95116

Safety of Dithiodipropionic acid

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H315-H318-H335-H410
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P330-P362+P364-P403+P233-P501
Class:9
UN#:3077
Packing Group:

Application In Synthesis of Dithiodipropionic acid

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1119-62-6 ]

[ 1119-62-6 ] Synthesis Path-Downstream   1~3

  • 2
  • [ 6414-69-3 ]
  • [ 1119-62-6 ]
  • 3
  • [ 1119-62-6 ]
  • [ 19008-43-6 ]
  • dibenzyl 4,4’-((3,3’-disulfanediylbis(propanoyl))bis(azanediyl))dibenzoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
With pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 10 - 50℃; for 12h; To a solution of 3-(2-carboxyethyldisulfanyl)propanoic acid (6.01 g, 28.60 mmol, I eq) and pyridine ( 14.93 g, 188.77 mmol, 15.24 mL, 6.6 eq) in DMF ( 120 L) was added EDCI ( 12.06 g, 62.92 mmol, 2.2 eq) and <strong>[19008-43-6]benzyl 4-aminobenzoate</strong> ( 13 g, 57.20 mmol, 2 eq) at 10C. Then, the mixture was stirred at 50C for 12 hrs. The residue was poured into ice-water (200 mL) and stirred for 20 min. The aqueous phase was extracted with ethyl acetate (200 mL*3). The combined organic phase was washed with sat. NaCI (200 mL*3), dried with anhydrous Na SCfi, filtered and concentrated in vacuum. Then, the residue was recrystallized from Petroleum ether:DCM = 50: 1 to get the solid. The solid was washed petroleum three times ( 150 ml * 3), and then dried in vacuum to give benzyl 4-[3-[[3-(4-benzyloxycarbonylanilino)-3-oxo-propyl]disulfanyl] propanoylamino]benzoate (14 g, crude) as a white solid; NMR (400MHz, DMSO-d6) d = 10.37 (s, 2H), 8.02 - 7.83 (m, 4H), 7.72 (d, J=8.8 Hz, 4H), 7.48 - 7.32 (m, 1 OH), 5.31 (s, 4H), 3.05 - 2.98 (m. 4H), 2.81 - 2.75 (m, 4H).
 

Historical Records

Technical Information

Categories