Cetrimonium bromide is a quaternary ammonium salt with surfactant and antimicrobial properties. Cetrimonium bromide is mainly used in cell culture, gene transfection, and antimicrobial research.

Synonyms: CTAB; Cetyltrimethylammonium bromide; Hexadecyltrimethylammonium bromide

4.5 *For Research Use Only !

{[proInfo.pro_purity]}

Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size	Price	VIP Price	US Stock	Global Stock	In Stock
{[ item.pr_size ]}		Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

{[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

Quality Control of Cetrimonium bromide Purity: 98% SDS Specification

COA

Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.

NMR

Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.

CNMR

Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.

HPLC

Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.

LC-MS

Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.

1-2 Day Shipping
High Quality
Technical Support

Product Citations

Green and Efficient Synthetic Protocol for 1, 3, 5-Triazine Derivatives with Anticancer Potential Against Colorectal Cancer

Chrzan, Julia ; Drabczyk, Anna Karolina ; Siemińska, Izabela ; Baj-Krzyworzeka, Monika ; Greber, Katarzyna Ewa ; Jaśkowska, Jolanta , et al.

DOI: 10.3390/molecules30112437 Molecules,2025,30(11):2437.

Abstract: Colorectal cancer (CRC) remains a major global health challenge, necessitating the development of more effective and environmentally sustainable treatments. This study presents a novel green synthetic protocol for 1,3,5-triazine derivatives with anticancer potential, employing both microwave-assisted and ultrasound-assisted methods. The synthesis was optimized using 4-chloro-N-(2-chlorophenyl)-6-(morpholin-4-yl)-1,3,5-triazin-2-amine as the key intermediate, with sodium carbonate, TBAB, and DMF providing optimal yields under microwave conditions. To enhance sustainability, a modified sonochemical method was also developed, enabling efficient synthesis in aqueous media with a minimal use of organic solvents. A series of nine morpholine-functionalized derivatives were synthesized and evaluated for cytotoxic activity against SW480 and SW620 colorectal cancer cell lines. Compound 11 demonstrated superior antiproliferative activity (IC₅₀ = 5.85 µM) compared to the reference drug 5-fluorouracil, while compound 5 showed promising dual-line activity. In silico ADME analysis supported the drug likeness of the synthesized compounds, and biomimetic chromatography analysis confirmed favorable physicochemical properties, including lipophilicity and membrane affinity. These results underscore the potential of the developed protocol to produce bioactive triazine derivatives through an efficient, scalable, and environmentally friendly process, offering a valuable strategy for future anticancer drug development.

Keywords: 1,3,5-triazine ; green chemistry ; microwave-assisted synthesis ; sonochemistry ; colorectal cancer ; anticancer agents ; phase-transfer catalysis ; cytotoxicity ; ADME ; drug likeness

Purchased from AmBeed: 56-37-1 ; 57-09-0 ; 1643-19-2

Product Details of Cetrimonium bromide

CAS No. :	57-09-0
Formula :	C₁₉H₄₂BrN
M.W :	364.45
SMILES Code :	CCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]
Synonyms :	CTAB; Cetyltrimethylammonium bromide; Hexadecyltrimethylammonium bromide
MDL No. :	MFCD00011772
InChI Key :	LZZYPRNAOMGNLH-UHFFFAOYSA-M
Pubchem ID :	5974

Safety of Cetrimonium bromide

GHS Pictogram:
Signal Word:	Danger
Hazard Statements:	H302-H315-H318-H335-H373-H400
Precautionary Statements:	P260-P280-P301+P312+P330-P305+P351+P338+P310
Class:	9
UN#:	3077
Packing Group:	Ⅲ

Application In Synthesis of Cetrimonium bromide

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 57-09-0 ]
Downstream synthetic route of [ 57-09-0 ]

[ 57-09-0 ] Synthesis Path-Upstream 1~2

1
[ 20098-38-8 ]
[ 57-09-0 ]
[ 1897-41-2 ]

References: [1] Patent: US4517129, 1985, A, .

2
[ 57-09-0 ]
[ 12582-61-5 ]

References: [1] Journal of the Chemical Society, Dalton Transactions, 2000, # 18, p. 3143 - 3148.

[ 57-09-0 ] Synthesis Path-Downstream 1~19

1
[ 1454-85-9 ]
[ 57-09-0 ]
C₁₉H₄₂N⁽¹⁺⁾*C₁₇H₃₆O*Br^(1-) [ No CAS ]

References: [1]Molecular Crystals and Liquid Crystals Science and Technology, Section A: Molecular Crystals and Liquid Crystals,1996,vol. 276-277,p. 139 - 143.

2
[ 20098-38-8 ]
[ 57-09-0 ]
[ 1897-41-2 ]

Yield	Reaction Conditions	Operation in experiment
	In chloroform; water;	EXAMPLE 1 1,2,4,5-Tetrachloro-3,6-dinitrobenzene (1.53 g, 0.005 mol), potassium cyanide (0.65 g, 0.01 mol), cetrimide (0.05 g), water (5 ml) and chloroform (5 ml) were stirred and heated under reflux (60° C.). Samples of the organic phase were removed at intervals and examined by glc analysis (5 ft column, 5percent OV 225). After 2 hours, there was estimated to be present in the chloroform a ca.90percent yield of tetrachloroterephthalodinitrile.

References: [1]Patent: US4517129,1985,A .

3
(Fe(C₆H₅)4C₂₀H₈N₄)2O⁽¹⁺⁾*SbF₆^(1-)=[(Fe(C₆H₅)4C₂₀H₈N₄)2O]SbF₆ [ No CAS ]
[ 57-09-0 ]
[ 12582-61-5 ]
tribromide [ No CAS ]

References: [1]Journal of the Chemical Society, Dalton Transactions,2000,p. 3143 - 3148.

4
[ 71-41-0 ]
[ 57-09-0 ]
[ 99532-45-3 ]
[ 19012-02-3 ]
[ 1226854-01-8 ]

References: [1]Synthesis,2010,p. 775 - 782.

5
[ 57-09-0 ]
[ 18194-24-6 ]
[ 61-73-4 ]
C₁₉H₄₂N⁽¹⁺⁾*Br^(1-)*C₃₆H₇₂NO₈P*C₃₄H₂₄N₆O₁₄S₄^(4-)*4Na⁽¹⁺⁾ [ No CAS ]