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Chemical Structure| 94-13-3 Chemical Structure| 94-13-3
Chemical Structure| 94-13-3

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Propylparaben, the n-propyl ester of p-hydroxybenzoic acid, occurs as a natural substance found in many plants and some insects

Synonyms: Propyl parahydroxybenzoate; Propyl 4-hydroxybenzoate; nipasol

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Product Details of Propylparaben

CAS No. :94-13-3
Formula : C10H12O3
M.W : 180.20
SMILES Code : O=C(OCCC)C1=CC=C(O)C=C1
Synonyms :
Propyl parahydroxybenzoate; Propyl 4-hydroxybenzoate; nipasol
MDL No. :MFCD00002354
InChI Key :QELSKZZBTMNZEB-UHFFFAOYSA-N
Pubchem ID :7175

Safety of Propylparaben

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H317-H319
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of Propylparaben

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 94-13-3 ]

[ 94-13-3 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 94-13-3 ]
  • [ 3101-60-8 ]
  • [ 60377-15-3 ]
  • 2
  • [ 120-47-8 ]
  • [ 94-13-3 ]
  • [ 94-26-8 ]
  • [ 94-18-8 ]
  • [ 4191-73-5 ]
  • [ 4247-02-3 ]
  • [ 108-24-7 ]
  • [ 99-76-3 ]
  • [ 27739-15-7 ]
  • [ 27801-52-1 ]
  • [ 27739-14-6 ]
  • [ 24262-66-6 ]
  • [ 13031-45-3 ]
  • [ 54835-09-5 ]
  • [ 27739-13-5 ]
  • 3
  • [ 94-13-3 ]
  • [ 41014-43-1 ]
  • propyl 4-(benzo[d]oxazol-2-ylmethoxy)benzoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
70.42% With potassium carbonate; In acetone; for 4h;Reflux; General procedure: To a solution of various substituted phenols (1 mmol) in dry acetone (30 mL) K2CO3 (1 mmol)and compound 3 or 4 (1 mmol) were added. After being stirred for 4 h at reflux temperature, thereaction mixture was cooled, filtered, and concentrated under vacuum. Then the residue was dilutedwith 30 mL ethyl acetate and sequentially washed with 30 mL 1 M HCl, aq. NaHCO3 solution andbrine in order. The organic layer was dried over MgSO4 and concentrated in vacuo. Purification of theresidue by chromatography on silica gel furnished target compounds. 1H-NMR, 13C-NMR and massspectroscopy (MS) of compounds 5a-m and 6a-m are shown in Supplementary Materials.
 

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