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Chemical Structure| 959972-34-0 Chemical Structure| 959972-34-0

Structure of 959972-34-0

Chemical Structure| 959972-34-0

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Product Details of [ 959972-34-0 ]

CAS No. :959972-34-0
Formula : C6H2ClIN2
M.W : 264.45
SMILES Code : N#CC1=CN=CC(I)=C1Cl
MDL No. :MFCD18262184

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Application In Synthesis of [ 959972-34-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 959972-34-0 ]

[ 959972-34-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 196205-06-8 ]
  • [ 959972-34-0 ]
  • [ 959972-35-1 ]
YieldReaction ConditionsOperation in experiment
75% In ethanol; for 72.0h;Heating / reflux; A mixture of 4-chloro-5-iodonicotinonitrile (5.0 g, 18.9 mmol) and <strong>[196205-06-8]5-amino-4-methylindole</strong> (3.0 g, 20.8 mmol) in EtOH (100 mL) was heated at reflux for 3 days, cooled to r.t and diluted with saturated aq. Na2SO4 (300 mL). The precipitated solids were collected by filtration, washed with water and dried to give 5.3 g (75%) of 5-iodo-4-[(4-methyl-1H-indol-5- yl)amino]nicotinonitrile as a grey solid, mp 192-1940C; MS (M+l-T): 375.1.
 

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