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Chemical Structure| 939986-76-2 Chemical Structure| 939986-76-2

Structure of 939986-76-2

Chemical Structure| 939986-76-2

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Product Details of [ 939986-76-2 ]

CAS No. :939986-76-2
Formula : C14H21ClN4O2
M.W : 312.80
SMILES Code : O=C(N1CCC(NC2=NC=NC(Cl)=C2)CC1)OC(C)(C)C
MDL No. :MFCD09607841

Safety of [ 939986-76-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 939986-76-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 939986-76-2 ]

[ 939986-76-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 387350-92-7 ]
  • [ 939986-76-2 ]
  • [ 1240301-00-1 ]
YieldReaction ConditionsOperation in experiment
62% To a solution of NaH (0.62 g, 15.5 mmol, 60% NaH) in 40 mL of DMF, 5- methanesulfonyl-2,3-dihydro-lH-indole (1.9 g, 9.63 mmol) was added and the mixture was stirred at room temperature for 30 minutes. 17a (3.09 g, 9.88 mmol) was added in DMF and the mixture was heated at 85 0C for 17h. After cooling to room temperature, brine was added (200 mL) and the mixture was extracted with DCM (200 mL then 3 x 500 mL). The combined extracts were washed with brine (3 x 100 mL), dried, filtered and evaporated. The residue was purified by flash chromatography (eluent : 25 to 100% EtOAc in hexane with 0.1% triethylamine) to afford 2.83 g (62 %) of 17b
 

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