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Chemical Structure| 924274-94-2 Chemical Structure| 924274-94-2

Structure of 924274-94-2

Chemical Structure| 924274-94-2

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Product Details of [ 924274-94-2 ]

CAS No. :924274-94-2
Formula : C6H5ClN2O3
M.W : 188.57
SMILES Code : OC1C(N)=C([N+](=O)[O-])C=C(Cl)C=1
MDL No. :MFCD27933066

Safety of [ 924274-94-2 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H315-H317-H318-H410
Precautionary Statements:P261-P264-P270-P272-P273-P280-P301+P312+P330-P302+P352-P305+P351+P338+P310-P333+P313-P391-P501
Class:9
UN#:3077
Packing Group:

Application In Synthesis of [ 924274-94-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 924274-94-2 ]

[ 924274-94-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 924274-94-2 ]
  • [ 74-88-4 ]
  • [ 859877-49-9 ]
YieldReaction ConditionsOperation in experiment
46.4% With potassium carbonate; In N,N-dimethyl-formamide; at 20℃; for 2h; Step 2. 4-Chloro-2-methoxy-6-nitroaniline. To a mixture of 2-amino-5- chloro-3-nitrophenol (752 mg, 4.0 mmol) and potassium carbonate (415 mg, 3.0 mmol) in DMF was added Mel (625 mg, 4.4 mmol). The reaction mixture was stirred at r.t. for 2hr, then quenched with water and extracted with EtOAc. Combined organic layers were washed with brine, dried over anhydrous Na2S04 and concentrated under reduced pressure. The residue was purified by flash column chromatography to give 4-chloro-2- methoxy- 6-nitroaniline (450 mg, 46.4% yield). LC-MS: m/z 203(M-H)+.
 

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