Home Cart Sign in  
Chemical Structure| 918431-93-3 Chemical Structure| 918431-93-3

Structure of 918431-93-3

Chemical Structure| 918431-93-3

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 918431-93-3 ]

CAS No. :918431-93-3
Formula : C11H17FN2O2
M.W : 228.26
SMILES Code : FC1(C#N)CCN(C(OC(C)(C)C)=O)CC1
MDL No. :MFCD19689456

Safety of [ 918431-93-3 ]

Application In Synthesis of [ 918431-93-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 918431-93-3 ]

[ 918431-93-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 918431-93-3 ]
  • [ 620611-27-0 ]
YieldReaction ConditionsOperation in experiment
tert-butyl 4-(aminomethyl)-4-fluoropiperidine-l-carboxylate (4-4); To a 0 C solution of 4-3 (8.83 g, 38.7 mmol) in 75 mL dry THF was added a solution of 1 M borane in THF (155 mL, 155 mmol) over 30 min. After 30 min more, the cold reaction was slowly quenched with EtOH (200 mL) and all solvent was removed in vacuo. The residue was taken up in saturated aq. NHtCl/EtOAc (150 mL) and extracted with EtOAc (3 x 150 mL). The organic layers were washed with 1 N aq. NaOH, brine, dried over MgSO4, filtered, and concentrated in vacuo, giving crude 4-4 as a pale yellow oil. The crude amine 4-4 was carried forward. 1H NMR (CDCl3, 300 MHz): 3.94 EPO <DP n="27"/>(br, 2H), 3.08 (m, 2H), 1.85 (m, 2H), 1.51 (m, 4H), 1.44 (s, 9H); MS (Electrospray): m/z 218.2 (M-Me+H), 177.2 (M-f-Bu+H).
  • 2
  • [ 614731-04-3 ]
  • [ 918431-93-3 ]
 

Historical Records

Technical Information

Categories