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Chemical Structure| 917388-58-0 Chemical Structure| 917388-58-0

Structure of 917388-58-0

Chemical Structure| 917388-58-0

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Product Details of [ 917388-58-0 ]

CAS No. :917388-58-0
Formula : C13H12BrNO3
M.W : 310.14
SMILES Code : O=C(C1=C(C2=CC=C(Br)C=C2)ON=C1C)OCC
MDL No. :MFCD20486244

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Application In Synthesis of [ 917388-58-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 917388-58-0 ]

[ 917388-58-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 917388-58-0 ]
  • [ 91182-60-4 ]
YieldReaction ConditionsOperation in experiment
96% To a stirred solution of ester (3.2 g, 0.010M) in THF/H2O (79/35 ml) was added lithium hydroxide (2.4 g, 0.010M). The reaction mixture was stirred at room temperature for over night and the solvent, THF was removed from the reaction mixture under vacuum. The resulting mass was diluted with water and washed with diethyl ether (2×50 ml). Then the aqueous solution was acidified with sat. Oxalic acid (PH4) and was extracted with ethyl acetate (2×75 ml). The combined organic layer was dried over anhydrous sodium sulphate, concentrated under vacuum to give the pure product 2.8 g (96%). 1H NMR (DMSO-d6): delta 2.52 (3H, s), 7.37 (2H, dd), 7.91 (2H, dd), 12.42 (1H, br s). 13C NMR (DMSO-d6) delta 12.0, 110.0, 126.6, 127.2, 131.7, 132.5, 162.4, 164.4, 172.7. MH+=282.
 

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