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Chemical Structure| 90408-82-5 Chemical Structure| 90408-82-5

Structure of 90408-82-5

Chemical Structure| 90408-82-5

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Product Details of [ 90408-82-5 ]

CAS No. :90408-82-5
Formula : C13H11IO2
M.W : 326.13
SMILES Code : OC1=C(I)C=CC(OCC2=CC=CC=C2)=C1
MDL No. :MFCD28128924

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Application In Synthesis of [ 90408-82-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 90408-82-5 ]

[ 90408-82-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 39604-97-2 ]
  • [ 90408-82-5 ]
  • [ 1431532-83-0 ]
YieldReaction ConditionsOperation in experiment
1.35 g With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N,N,N',N'-tetramethylguanidine; In N,N-dimethyl-formamide; at 60℃; for 0.5h;Inert atmosphere; B) 6-(benzyloxy)-2-(4-propoxyphenyl)-1-benzofuran To a solution of 5-(benzyloxy)-2-iodophenol (2.65 g), <strong>[39604-97-2]4-propoxyphenylacetylene</strong> (1.97 g) and 1,1,3,3-tetramethylguanidine (3.08 mL) in DMF (15 mL) were added bistriphenylphosphinedichloropalladium(II) (288 mg) and copper(I) iodide (156 mg) under a nitrogen atmosphere, and the mixture was stirred at 60 C. for 30 min. The reaction mixture was diluted with ethyl acetate, washed with water and saturated brine, and dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (hexane/ethyl acetate) to give the title compound (1.35 g). 1H NMR (300 MHz, CDCl3) delta 1.05 (3H, t, J=7.5 Hz), 1.80-1.87 (2H, m), 3.97 (2H, t, J=6.4 Hz), 5.12 (2H, s), 6.80 (1H, s), 6.91-6.97 (3H, m), 7.12 (1H, s), 7.33-7.49 (6H, m), 7.72 (2H, d, J=8.7 Hz).
 

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