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Chemical Structure| 897922-06-4 Chemical Structure| 897922-06-4

Structure of 897922-06-4

Chemical Structure| 897922-06-4

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Product Details of [ 897922-06-4 ]

CAS No. :897922-06-4
Formula : C7H7BrO2S
M.W : 235.10
SMILES Code : BrCC1COC2=CSC=C2O1

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Application In Synthesis of [ 897922-06-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 897922-06-4 ]

[ 897922-06-4 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 51792-34-8 ]
  • [ 4704-77-2 ]
  • [ 897922-06-4 ]
YieldReaction ConditionsOperation in experiment
57% With toluene-4-sulfonic acid; In toluene; at 100℃; EXAMPLE 2: Conversion of 3, 4-dimethoxythiophene to 2-(bromomethyI)-2, 3-dihydrothieno[3,4-][l,4]dioxine; [0086] Under nitrogen, 20.0 g (0.139 mol) dimethoxythiophene, 25.0 g (0.161 mol) 3-bromo-l,2-propanediol, and 5 g p-toluenesulfonic acid was combined with 350 mL toluene in a 500 mL round bottom flask equipped with a reflux condenser and stir bar. The reaction mixture was sparged with nitrogen for 30 minutes then heated to 100 C overnight. Upon cooling to room temperature the reaction mixture was concentrated to -100 mL and poured into saturated potassium carbonate solution. The resulting solution was extracted with DCM. The combined extracts were washed with brine, then dried with magnesium sulfate. Solvent removal gave a black oil. The crude material was purified by column chromatography using 3: 1 hexanes/DCM. Solvent removal gave a white solid that was dried under high vacuum overnight to give 18.6 g of material. The structure and purity were confirmed by 1H/I 3C NMR and GC-MS. Yield was 57percent of theoretical.
  • 2
  • [ 897922-06-4 ]
  • [ 117-78-2 ]
  • C22H14O6S [ No CAS ]
 

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