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Chemical Structure| 89760-42-9 Chemical Structure| 89760-42-9

Structure of 89760-42-9

Chemical Structure| 89760-42-9

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Product Details of [ 89760-42-9 ]

CAS No. :89760-42-9
Formula : C11H11FO2
M.W : 194.20
SMILES Code : O=C(OCC)/C=C/C1=CC=CC=C1F
MDL No. :MFCD03095007

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Application In Synthesis of [ 89760-42-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 89760-42-9 ]

[ 89760-42-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 18944-77-9 ]
  • [ 89760-42-9 ]
YieldReaction ConditionsOperation in experiment
54.25 g (96%) With thionyl chloride; In ethanol; ethyl acetate; a) Preparation of Ethyl 2-Fluorocinnamate A solution of <strong>[18944-77-9]2-fluorocinnamic acid</strong> (48.4 g, 0.29 mol, Aldrich) and thionyl chloride (5 mL) in ethanol (650 mL) was heated to reflux for 48 h. The mixture was concentrated in vacuo. The residue was taken up in ethyl acetate, washed successively with a 5% aqueous sodium bicarbonate solution, water and brine, and dried (Na2 SO4). Filtration and concentration gave 54.25 g (96%) of crude ethyl 2-fluorocinnamate. This material was used without further purification.
 

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