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Chemical Structure| 878799-20-3 Chemical Structure| 878799-20-3

Structure of 1-Boc-amino-butyl-3-amine
CAS No.: 878799-20-3

Chemical Structure| 878799-20-3

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Product Details of [ 878799-20-3 ]

CAS No. :878799-20-3
Formula : C9H20N2O2
M.W : 188.27
SMILES Code : O=C(OC(C)(C)C)NCCC(N)C
MDL No. :MFCD06804533
InChI Key :MSCLVLGMLLYXFV-UHFFFAOYSA-N
Pubchem ID :45072485

Safety of [ 878799-20-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P280-P305+P351+P338-P310
Class:8
UN#:1760
Packing Group:

Application In Synthesis of [ 878799-20-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 878799-20-3 ]

[ 878799-20-3 ] Synthesis Path-Downstream   1~7

  • 1
  • [ 878799-20-3 ]
  • [ 85958-57-2 ]
  • [ 878799-21-4 ]
YieldReaction ConditionsOperation in experiment
74% With triethylamine; In dichloromethane; at 20℃; for 2.0h; To a solution of 1 ,1 -dimethylethyl (3-aminobutyl)carbamate (0.10 g, 0.53 mmol) in CH2CI2 (5 ml_) were added 2-chloro-4-fluorobezenesulfonyl chloride (0.15 g, 0.64 mmol) and Et3N (0.22 ml_, 1.60 mmol) at rt. After 2 hr at rt, the reaction mixture was concentrated and purified by flash column chromatography on silica gel (Biotage, 5%-40% EtOAc/hexane) to provide 0.15g (74%) of the title compound.
  • 2
  • [ 878799-19-0 ]
  • [ 878799-20-3 ]
YieldReaction ConditionsOperation in experiment
90% With hydrogen;palladium 10% on activated carbon; In ethanol; at 20℃; under 760.051 Torr; for 5.0h; To the solution of 1 ,1 -dimethylethyl phenylmethyl 1 ,3-butanediylbiscarbamate (0.19 g, 0.59 mmol) in 5 ml of EtOH was added 30 mg of 10% Pd on carbon under N2. The reaction mixture was stirred under H2 atmosphere (1 atm) at room temperature for 5 hours. The solution was filtered and concentrated to give 0.10 g of the title product (90%).
  • 4
  • [ 6627-89-0 ]
  • [ 590-88-5 ]
  • [ 878799-20-3 ]
  • 5
  • [ 86-98-6 ]
  • [ 878799-20-3 ]
  • [ 1349530-48-8 ]
  • 6
  • [ 878799-20-3 ]
  • [ 501-53-1 ]
  • C16H24N2O4 [ No CAS ]
  • 7
  • [ 878799-20-3 ]
  • [ 98-59-9 ]
  • tert-butyl (3-((4-methylphenyl)sulfonamido)butyl)carbamate [ No CAS ]
YieldReaction ConditionsOperation in experiment
With sodium carbonate; sodium chloride; In dichloromethane; for 1.0h; To <strong>[878799-20-3]tert-butyl (3-aminobutyl)carbamate</strong> (2.5 g, 13.3 mmol) in DCM (12.5 ml_), sat. Na2C03 (12.5 mL), and sat. NaCI (12.5 ml.) was added TsCI (13.3 mmol, 2.54 g). After 1 h the organic layer was washed with brine, dried with sodium sulfate, filtered, and concentrated to provide tert-butyl (3-((4-methylphenyl)sulfonamido)butyl)carbamate which was carried forward without further purification.
 

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