Home Cart Sign in  
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 869569-77-7 Chemical Structure| 869569-77-7

Structure of 869569-77-7

Chemical Structure| 869569-77-7

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 869569-77-7 ]

CAS No. :869569-77-7
Formula : C8H5Br2FO
M.W : 295.93
SMILES Code : FC1=C(C=CC(Br)=C1)C(=O)CBr
MDL No. :MFCD11847024
InChI Key :HDDUJSBRWLHLME-UHFFFAOYSA-N
Pubchem ID :22121483

Safety of [ 869569-77-7 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 869569-77-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 869569-77-7 ]

[ 869569-77-7 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 334769-80-1 ]
  • [ 869569-77-7 ]
  • [ 1393537-71-7 ]
YieldReaction ConditionsOperation in experiment
With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20℃; for 64h; To a solution of Example 4, step a (2.58 g, 8.72 mmol) and (2S,5S)-l-(tert- butoxycarbonyl)-5-methylpyrrolidine-2-carboxylic acid (2.00 g, 8.72 mmol) in acetonitrile (50 mL) was added DIEA (2.285 mL, 13.08 mmol), and the mixture was stirred at room temperature for 64 hrs. Solvent was removed in vacuo and the residue was partitioned between EtOAc (40 mL) and water (30 mL). The organic layer was washed with sat. aHC03 and brine, dried with a2S04 and evaporated in vacuo to afford Example 4, step b (3.8 g) as yellow solid. 1H NMR (CDC13, 400 MHz): 7.87 (m, 1H), 7.44 (m, 2H), 5.42-5.09 (m, 2H), 4.53-4.40 (m, 1H), 4.10-3.95 (m, 1H), 2.31 (m, 2H), 2.09 (m, 1H), 1.75 (m, 1H), 1.49-1.46 (two singlet, 9H), 1.33 (m, 3H). LC/MS: Anal. Calcd. for [M+Na]+ Ci9H24BrNNa05: 466.06; found: 466.03.
With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20℃; for 64h; Exam le QC-18.1, step bTo a solution of Example 18.1, step a (2.58 g, 8.72 mmol) and (2S,5S)-l-(tert- butoxycarbonyl)-5-methylpyrrolidine-2-carboxylic acid (2.00 g, 8.72 mmol) in acetonitrile (50 mL) was added DIEA (2.285 mL, 13.08 mmol), and the mixture was stirred at room temperature for 64 hrs. Solvent was removed in vacuo and the residue was partitioned between EtOAc (40 mL) and water (30 mL). The organic layer was washed with sat. aHC03 and brine, dried with Na2S04 and evaporated in vacuo to afford Example 18.1, step b (3.8 g) as yellow solid. XH NMR (CDC13, 400 MHz): 7.87 (m, 1H), 7.44 (m, 2H), 5.42-5.09 (m, 2H), 4.53-4.40 (m, 1H), 4.10-3.95 (m, 1H), 2.31 (m, 2H), 2.09 (m, 1H), 1.75 (m, 1H), 1.49-1.46 (two singlet, 9H), 1.33 (m, 3H). LC/MS: Anal. Calcd. for [M+Naf 466.06; found: 466.03.
  • 2
  • [ 334769-80-1 ]
  • [ 869569-77-7 ]
  • C19H23BrFNO5 [ No CAS ]
YieldReaction ConditionsOperation in experiment
3.8 g With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20℃; for 64h; To a solution of Example 18.1, step a (2.58 g, 8.72 mmol) and (2S,5S)-l-(tert- butoxycarbonyl)-5-methylpyrrolidine-2-carboxylic acid (2.00 g, 8.72 mmol) in acetonitrile (50 mL) was added DIEA (2.285 mL, 13.08 mmol), and the mixture was stirred at room temperature for 64 h. Solvent was removed in vacuo and the residue was partitioned between EtOAc (40 mL) and water (30 mL). The organic layer was washed with sat. NaHC03 and brine, dried with Na2SO4 and evaporated in vacuo to afford Example 18.1, step b (3.8 g) as yellow solid. 1H NMR (CDCl3, 400 MHz): 7.87 (m, 1H), 7.44 (m, 2H), 5.42-5.09 (m, 2H), 4.53-4.40 (m, 1H), 4.10-3.95 (m, 1H), 2.31 (m, 2H), 2.09 (m, 1H), 1.75 (m, 1H), 1.49-1.46 (two singlet, 9H), 1.33 (m, 3H). LC/MS: Anal. Calcd. for [M+Naf 466.06; found: 466.03
  • 3
  • [ 364750-81-2 ]
  • [ 869569-77-7 ]
  • C19H23BrFN3O2 [ No CAS ]
 

Historical Records

Technical Information

• Alkyl Halide Occurrence • Arndt-Eistert Homologation • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Bucherer-Bergs Reaction • Clemmensen Reduction • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Fischer Indole Synthesis • General Reactivity • Grignard Reaction • Henry Nitroaldol Reaction • Hiyama Cross-Coupling Reaction • Horner-Wadsworth-Emmons Reaction • Hunsdiecker-Borodin Reaction • Hydride Reductions • Kinetics of Alkyl Halides • Kumada Cross-Coupling Reaction • Lawesson's Reagent • Leuckart-Wallach Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Amines • Preparation of Carboxylic Acids • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Alkyl Halides with Reducing Metals • Reactions of Amines • Reactions of Benzene and Substituted Benzenes • Reactions of Carboxylic Acids • Reactions of Dihalides • Reformatsky Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Ketenes • Stille Coupling • Stobbe Condensation • Substitution and Elimination Reactions of Alkyl Halides • Suzuki Coupling • Tebbe Olefination • Ugi Reaction • Wittig Reaction • Wolff-Kishner Reduction

Categories

Related Functional Groups of
[ 869569-77-7 ]

Fluorinated Building Blocks

Chemical Structure| 928715-37-1

A215659 [928715-37-1]

1-(2-Bromo-6-fluorophenyl)ethanone

Similarity: 0.88

Chemical Structure| 1242157-14-7

A651351 [1242157-14-7]

5-Bromo-7-fluoro-2,3-dihydro-1H-inden-1-one

Similarity: 0.88

Chemical Structure| 161957-61-5

A207550 [161957-61-5]

1-(3-Bromo-2-fluorophenyl)ethanone

Similarity: 0.88

Chemical Structure| 174603-56-6

A113575 [174603-56-6]

4-Bromo-6-fluoro-2,3-dihydro-1H-inden-1-one

Similarity: 0.85

Chemical Structure| 1260018-37-8

A259330 [1260018-37-8]

5-Bromo-7-fluoro-3,4-dihydronaphthalen-1(2H)-one

Similarity: 0.85

Aryls

Chemical Structure| 928715-37-1

A215659 [928715-37-1]

1-(2-Bromo-6-fluorophenyl)ethanone

Similarity: 0.88

Chemical Structure| 1242157-14-7

A651351 [1242157-14-7]

5-Bromo-7-fluoro-2,3-dihydro-1H-inden-1-one

Similarity: 0.88

Chemical Structure| 161957-61-5

A207550 [161957-61-5]

1-(3-Bromo-2-fluorophenyl)ethanone

Similarity: 0.88

Chemical Structure| 174603-56-6

A113575 [174603-56-6]

4-Bromo-6-fluoro-2,3-dihydro-1H-inden-1-one

Similarity: 0.85

Chemical Structure| 1260018-37-8

A259330 [1260018-37-8]

5-Bromo-7-fluoro-3,4-dihydronaphthalen-1(2H)-one

Similarity: 0.85

Bromides

Chemical Structure| 928715-37-1

A215659 [928715-37-1]

1-(2-Bromo-6-fluorophenyl)ethanone

Similarity: 0.88

Chemical Structure| 1242157-14-7

A651351 [1242157-14-7]

5-Bromo-7-fluoro-2,3-dihydro-1H-inden-1-one

Similarity: 0.88

Chemical Structure| 161957-61-5

A207550 [161957-61-5]

1-(3-Bromo-2-fluorophenyl)ethanone

Similarity: 0.88

Chemical Structure| 174603-56-6

A113575 [174603-56-6]

4-Bromo-6-fluoro-2,3-dihydro-1H-inden-1-one

Similarity: 0.85

Chemical Structure| 1260018-37-8

A259330 [1260018-37-8]

5-Bromo-7-fluoro-3,4-dihydronaphthalen-1(2H)-one

Similarity: 0.85

Ketones

Chemical Structure| 928715-37-1

A215659 [928715-37-1]

1-(2-Bromo-6-fluorophenyl)ethanone

Similarity: 0.88

Chemical Structure| 1242157-14-7

A651351 [1242157-14-7]

5-Bromo-7-fluoro-2,3-dihydro-1H-inden-1-one

Similarity: 0.88

Chemical Structure| 161957-61-5

A207550 [161957-61-5]

1-(3-Bromo-2-fluorophenyl)ethanone

Similarity: 0.88

Chemical Structure| 174603-56-6

A113575 [174603-56-6]

4-Bromo-6-fluoro-2,3-dihydro-1H-inden-1-one

Similarity: 0.85

Chemical Structure| 1260018-37-8

A259330 [1260018-37-8]

5-Bromo-7-fluoro-3,4-dihydronaphthalen-1(2H)-one

Similarity: 0.85