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Chemical Structure| 86749-03-3 Chemical Structure| 86749-03-3

Structure of 86749-03-3

Chemical Structure| 86749-03-3

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Product Details of [ 86749-03-3 ]

CAS No. :86749-03-3
Formula : C14H16N2S2
M.W : 276.42
SMILES Code : NC1=C(SSC2=C(C(C)=CC=C2)N)C=CC=C1C

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Application In Synthesis of [ 86749-03-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 86749-03-3 ]

[ 86749-03-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 75-15-0 ]
  • [ 86749-03-3 ]
  • [ 10544-50-0 ]
  • [ 2268-77-1 ]
  • 2
  • [ 75-15-0 ]
  • [ 86749-03-3 ]
  • [ 2268-77-1 ]
YieldReaction ConditionsOperation in experiment
85.8% With sodium hydrogen sulfide; In water; at 80℃; for 9h;Green chemistry; To the reaction flask was added 11 lmg (0.40 mmol) of 6,6'-dimethyl-2,2'-dithiodiphenamine and 11.2 mg (0.2 mmol) of NaHS followed by 2.5 mL of H20 As a reaction solvent, and then injected into 97yL (l · 6mmol) of carbon disulfide, the reaction was stirred at 80 C for 9 hours after plate chromatography detected disulfide raw material was completely reacted, cooled to room temperature, extracted with ethyl acetate, The solvent was removed under reduced pressure on a rotary evaporator to give the crude product. The crude product was eluted with methylene chloride and eluted with a gradient. The residue was purified by column chromatography (200300 mesh silica gel) to give 124.4 mg of 4-methyl-2-mercaptobenzothiazole as white powder with a purity of more than 99% Isolated yield 85.8%, mp 191-193 C
 

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