Home Cart Sign in  
Chemical Structure| 862574-89-8 Chemical Structure| 862574-89-8

Structure of 862574-89-8

Chemical Structure| 862574-89-8

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 862574-89-8 ]

CAS No. :862574-89-8
Formula : C11H10O4
M.W : 206.19
SMILES Code : O=C(C1(C2=CC=C(OCO3)C3=C2)CC1)O
MDL No. :MFCD09907922
InChI Key :NZZVDTIYQUASAT-UHFFFAOYSA-N
Pubchem ID :14349608

Safety of [ 862574-89-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 862574-89-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 862574-89-8 ]

[ 862574-89-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 862574-89-8 ]
  • [ 30709-67-2 ]
  • 1-(benzo[d][1,3]dioxol-5-yl)-N-(5-methyl-4-phenylthiazol-2-yl)cyclopropanecarboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
51% With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 19h; General procedure: The benzo [1, 3] dioxol-5-yl-cyclopropanecarboxylic acid (1 eq) was resuspended in anhydrous DMF (1ml), HBTU (1 eq) and DIPEA (1 eq) were added. The reaction was vigorously stirred for 5min and the appropriate thiazole or aminic derivative (1 eq) in anhydrous DMF (500μL) was added, and the reaction was kept at T=40C until completeness (from 14h to 24h) depending from reactants. The mixture was concentrated under vacuum and after extraction with organic solvent (3×3ml), washed with H2O (3×2ml). The organic phases were dried over Na2SO4 and concentrated under reduced pressure and concentrated under vacuum. The crude product was then purified by preparative HPLC; the peak of interest was concentrated in vacuum and finally lyophilized to obtain the final compound.
  • 2
  • [ 862574-89-8 ]
  • [ 30748-47-1 ]
  • N-(5-acetyl-4-methylthiazol-2-yl)-1-(benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
71% With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 10h; General procedure: The benzo [1, 3] dioxol-5-yl-cyclopropanecarboxylic acid (1 eq) was resuspended in anhydrous DMF (1ml), HBTU (1 eq) and DIPEA (1 eq) were added. The reaction was vigorously stirred for 5min and the appropriate thiazole or aminic derivative (1 eq) in anhydrous DMF (500μL) was added, and the reaction was kept at T=40C until completeness (from 14h to 24h) depending from reactants. The mixture was concentrated under vacuum and after extraction with organic solvent (3×3ml), washed with H2O (3×2ml). The organic phases were dried over Na2SO4 and concentrated under reduced pressure and concentrated under vacuum. The crude product was then purified by preparative HPLC; the peak of interest was concentrated in vacuum and finally lyophilized to obtain the final compound.
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 862574-89-8 ]

Carboxylic Acids

Chemical Structure| 16728-01-1

A139043 [16728-01-1]

1-(4-Methoxyphenyl)cyclopropanecarboxylic acid

Similarity: 0.84

Chemical Structure| 862574-88-7

A201464 [862574-88-7]

1-(2,2-Difluorobenzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid

Similarity: 0.83

Chemical Structure| 43050-39-1

A173479 [43050-39-1]

1-(3-Methoxyphenyl)cyclopentanecarboxylic acid

Similarity: 0.82

Chemical Structure| 116854-10-5

A116416 [116854-10-5]

5-Methoxy-2,3-dihydro-1H-indene-1-carboxylic acid

Similarity: 0.80

Chemical Structure| 2955-46-6

A264975 [2955-46-6]

2-(4-Methoxyphenyl)-2-methylpropanoic acid

Similarity: 0.80

Related Parent Nucleus of
[ 862574-89-8 ]

Other Aromatic Heterocycles

Chemical Structure| 862574-88-7

A201464 [862574-88-7]

1-(2,2-Difluorobenzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid

Similarity: 0.83

Chemical Structure| 94-53-1

A251901 [94-53-1]

Benzo[d][1,3]dioxole-5-carboxylic acid

Similarity: 0.78

Chemical Structure| 5768-39-8

A121519 [5768-39-8]

Benzo[d][1,3]dioxole-4-carboxylic acid

Similarity: 0.75

Chemical Structure| 63740-97-6

A184479 [63740-97-6]

1-(Benzo[d][1,3]dioxol-5-yl)butan-1-one

Similarity: 0.75

Chemical Structure| 81581-27-3

A219639 [81581-27-3]

Ethyl 3-(benzo[d][1,3]dioxol-5-yl)-3-oxopropanoate

Similarity: 0.74