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Chemical Structure| 855784-42-8 Chemical Structure| 855784-42-8

Structure of 855784-42-8

Chemical Structure| 855784-42-8

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Product Details of [ 855784-42-8 ]

CAS No. :855784-42-8
Formula : C7H9N3O2
M.W : 167.17
SMILES Code : O=C(C1=NC(OC)=CC=C1)NN
MDL No. :MFCD08235125
InChI Key :GMZSCQXNOIDMCL-UHFFFAOYSA-N
Pubchem ID :24229172

Safety of [ 855784-42-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H319
Precautionary Statements:P305+P351+P338

Application In Synthesis of [ 855784-42-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 855784-42-8 ]

[ 855784-42-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1520-70-3 ]
  • [ 855784-42-8 ]
  • [ 343790-65-8 ]
  • (Z)-N'-(2,6-dimethoxyphenyl)-2-(6-methoxypicolinoyl)-N-(methylsulfonyl)hydrazinecarboximidamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
94% (Z)-N?-(2,6-dimethoxyphenyl)-2-(6-methoxypicolinoyl)-N- (methylsulfonyl)hydrazinecarboximidamide, Example 5.01. To a solution of 2- isothiocyanato-1,3-dimethoxybenzene (Example 1.0, 3.90 g, 20.0 mmol) and ethyl sulfonamide (1.81 mL, 21.0 mmol) in ACN (100 mL) at ambient temperature, was added cesium carbonate (8.46 g, 26.0 mmol) in one portion. The reaction was stirred over the weekend. To the mixture was added 6-methoxypicolinohydrazide (3.51 g, 21.0 mmol) in one portion followed by silver(I) nitrate (6.79 g, 40.0 mmol). The mixture was stirred for 15 mm. The material obtained was absorbed onto a plug of silica gel and purified by chromatography through a Redi-Sep pre-packed silica gel column (40 g), eluting with a gradient of 0-100percent B/A (B = 15percent MeOWDCM, A = DCM), to provide the title compound 5.01 (8.22 g, 18.8 mmol, 94percent yield) as an off-white powder. LCMS-ESI (POS.) m/z: 438.2 (M+H).
 

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Technical Information

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Related Functional Groups of
[ 855784-42-8 ]

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