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Chemical Structure| 850363-52-9 Chemical Structure| 850363-52-9

Structure of 850363-52-9

Chemical Structure| 850363-52-9

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Product Details of [ 850363-52-9 ]

CAS No. :850363-52-9
Formula : C9H7IN2O
M.W : 286.07
SMILES Code : CC(N1N=CC2=C1C=C(I)C=C2)=O
MDL No. :MFCD26227254

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Application In Synthesis of [ 850363-52-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 850363-52-9 ]

[ 850363-52-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 850363-52-9 ]
  • [ 261953-36-0 ]
YieldReaction ConditionsOperation in experiment
78% To a solution of step-d product (12 g, 0.04 mol) in 1 ,4-dioxane (60 ml, 5 times), 6N HCI (60 ml, 5 times) was added at rt. Reaction mixture was heated to 7O0C and allowed to stir for 2 hrs at the same temperature. Progress of the reaction was monitored by TLC (30% ethyl acetate/hexane, Rf-0.5). On completion of the reaction, 1 ,4-dioxane was distilled off completely, residue obtained was basified to a pH-12 -13 with sodium hydroxide solution and the compound extracted with ethyl acetate (2 * 75 ml). Combined extract was dried over sodium sulfate and concentrated under reduced pressure to yield the required product (10 g, 78% yield).
 

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