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Chemical Structure| 84713-20-2 Chemical Structure| 84713-20-2

Structure of 84713-20-2

Chemical Structure| 84713-20-2

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Product Details of [ 84713-20-2 ]

CAS No. :84713-20-2
Formula : C10H11NO2
M.W : 177.20
SMILES Code : O=C(OCC1=CC=CC=C1)NC=C
MDL No. :MFCD04114067
InChI Key :YGBQZFPEMRCQRY-UHFFFAOYSA-N
Pubchem ID :10931982

Safety of [ 84713-20-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 84713-20-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 84713-20-2 ]

[ 84713-20-2 ] Synthesis Path-Downstream   1~6

  • 1
  • [ 84713-20-2 ]
  • [ 4540-87-8 ]
  • 2
  • [ 84713-20-2 ]
  • [ 22802-67-1 ]
  • [ 75-07-0 ]
  • cis-4-benzyloxycarbonylamino-6-methoxy-2-methyl-1,2,3,4-tetrahydro-quinoline-7-carboxylic acid methyl ester [ No CAS ]
YieldReaction ConditionsOperation in experiment
With BF3-etherate; sodium sulfate; In dichloromethane; Example 1 cis-4-Benzyloxycarbonylamino-6-methoxy-2-methyl-1,2,3,4-tetrahydro-quinoline-7-carboxylic acid methyl ester. To a solution of 4.26 g <strong>[22802-67-1]methyl 2-methoxy-5-aminobenzoate</strong> (23.5 mmol) in 65 ml anhydrous dichloromethane was added 3.34 g anhydrous sodium sulfate, and the resulting mixture was cooled to -25 C. Freshly distilled acetaldehyde (1.04 g, 23.5 mmol) was added and the mixture was stirred at -25 C. for 2 h. The supernatant was cannulated into a -25 C. solution of N-vinyl-O-benzyl carbamate (1.4 g, 7.8 mmol) in 10 ml dichloromethane. BF3-etherate (111 mg, 0.78 mmol) was added over 10 min, and the the reaction was stirred at -25 C. for 1.5 h. The reaction was quenched cold with the addition of an aqueous 10% sodium sulfate solution. The aqueous phase was separated and was extracted with dichloromethane (100 mL). The combined organic layers were dried (MgSO4), filtered and concentrated, and the crude material was purified by silica gel chromatography using dichloromethane to afford the title product (0.99 g). 1 H NMR (DMSO-d6) δ 1.13 (d, 3H), 6.58 (s, 1H).
  • 3
  • [ 114046-25-2 ]
  • [ 84713-20-2 ]
  • [ 1140966-25-1 ]
  • 4
  • [ 114046-25-2 ]
  • [ 84713-20-2 ]
  • [2-(4-cyano-phenyl)-6-methoxy-1,2,3,4-tetrahydro-quinolin-4-yl]-carbamic acid benzyl ester [ No CAS ]
  • 5
  • [ 84713-20-2 ]
  • [ 35691-20-4 ]
  • [ 1220596-44-0 ]
  • 6
  • [ 1018446-96-2 ]
  • [ 84713-20-2 ]
  • [ 80565-30-6 ]
  • [ 1630985-00-0 ]
 

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