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Chemical Structure| 845866-80-0 Chemical Structure| 845866-80-0

Structure of 845866-80-0

Chemical Structure| 845866-80-0

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Product Details of [ 845866-80-0 ]

CAS No. :845866-80-0
Formula : C3H4ClF3O2S
M.W : 196.58
SMILES Code : O=S(CCC(F)(F)F)(Cl)=O
MDL No. :MFCD06248898
InChI Key :OXKHPRFGCFJUSK-UHFFFAOYSA-N
Pubchem ID :2761177

Safety of [ 845866-80-0 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P280-P305+P351+P338-P310
Class:8
UN#:3265
Packing Group:

Application In Synthesis of [ 845866-80-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 845866-80-0 ]

[ 845866-80-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 845866-80-0 ]
  • [ 120100-15-4 ]
  • [ 1307272-31-6 ]
YieldReaction ConditionsOperation in experiment
With pyridine; at 20℃; for 40h;Inert atmosphere; To a solution of <strong>[120100-15-4]methyl 3-amino-2-chlorobenzoate</strong> (20 g, 108 mmol) in pyridine (300 ml_) was added dropwise a solution of 3,3,3-trifluoro-1 - propanesulfonyl chloride (21 .18 g, 108 mmol) in 30 ml_ of pyridine. After 16 hours at room temperature, 3, 3,3-trifluoro-1 -propanesulfonyl chloride (4 g) was added to the reaction mixture. After another 24 hours, the reaction solution was concentrated. The crude residue was partioned between EtOAc and water. The phases were separated. The aqueous phase was further extracted with EtOAc twice more and the combined organic phases were washed with 1 N HCI, water, brine and dried over MgSO4, filtered and concentrated to obtain title compound.
 

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[ 845866-80-0 ]

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