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Chemical Structure| 83710-61-6 Chemical Structure| 83710-61-6

Structure of 83710-61-6

Chemical Structure| 83710-61-6

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Product Details of [ 83710-61-6 ]

CAS No. :83710-61-6
Formula : C11H9BrO
M.W : 237.09
SMILES Code : COC1=CC2=C(Br)C=CC=C2C=C1
MDL No. :MFCD07435364
InChI Key :COLPPPMPHPHUPC-UHFFFAOYSA-N
Pubchem ID :13025836

Safety of [ 83710-61-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362

Application In Synthesis of [ 83710-61-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 83710-61-6 ]

[ 83710-61-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 83710-61-6 ]
  • [ 590-17-0 ]
  • [ 138113-08-3 ]
YieldReaction ConditionsOperation in experiment
94.6% The (26.4g, 1.1mol) magnesium chips and 0.1g iodine placed in 2L three-necked flask,And add 60ml of tetrahydrofuran Stir the 1-bromo-7-methoxynaphthalene (237.1g, 1.0mol) was added to 360ml of tetrahydrofuran in a dropping funnel to make a mixed solution, a few drops slowly to the reaction flask with stirring After 5 min, the solution in the reaction flask was slightly boiled and cooled in an ice-water bath to 5 C. 360 ml of tetrahydrofuran was added to the reaction flask, and the mixture prepared above was added dropwise under stirring to control the reaction temperature at 38 C.,The reaction time 2h to give 1-bromo-7-methoxy-naphthalene testThe reaction solution.(132.0 g, 1.1 mol) of bromoacetonitrile was added to 360 ml of tetrahydrofuran to prepare a mixture of bromoacetonitrile and the resultingThe reaction solution of 1-bromo-7-methoxy-Naphthalene reagent was cooled to 0 C in a reaction flask. The prepared mixed solution of bromoacetonitrile was slowly added dropwise to the reaction flask with stirring. After the dropwise addition, the temperature was raised to 55 C The reaction was carried out for 2h to obtain a reaction solution of (7-methoxy-1-naphthyl) acetonitrile. The reaction solution of the obtained (7-methoxy-1-naphthyl) acetonitrile was cooled to 25 C and added with a mass fraction of 10% Salt water to terminate the reaction, and then separated, dried and concentrated to 360ml of tetrahydrofuran, and then cooled crystallization, after filtration, 50 C blast drying186.7g(7-methoxy-1-naphthyl) acetonitrile, yield 94.6%, purity 99.1%.
 

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