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Chemical Structure| 80221-11-0 Chemical Structure| 80221-11-0

Structure of 80221-11-0

Chemical Structure| 80221-11-0

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Product Details of [ 80221-11-0 ]

CAS No. :80221-11-0
Formula : C22H26
M.W : 290.44
SMILES Code : CCCCC1=CC=C(C#CC2=CC=C(CCCC)C=C2)C=C1
MDL No. :MFCD04038794

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Application In Synthesis of [ 80221-11-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 80221-11-0 ]

[ 80221-11-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 20651-67-6 ]
  • [ 79887-09-5 ]
  • [ 80221-11-0 ]
  • 2
  • [ 80221-11-0 ]
  • [ 13304-62-6 ]
  • 2,6-dibenzyl-3,4,7,8-tetrakis(4-butylphenyl)-2,6-dihydro-2,6-naphthyridin-1,5-dione [ No CAS ]
YieldReaction ConditionsOperation in experiment
61% With potassium hexafluorophosphate; dirhodium tetraacetate; silver carbonate; In 1,4-dioxane; at 20℃;Reflux; The preparation method is as follows: Add a N-benzyl acrylamide dioxane solution to a clean 30 mL round bottom flask with stirring magnets at a concentration of 1 M. Then adding the catalyst cerium acetate (10 mol%), Oxidant silver carbonate (3 eq), additive potassium hexafluorophosphate (0.5 eq), 1,2-bis(4-butylphenyl)acetylene (1.0 eq). This mixture was stirred at room temperature for one hour and then heated to reflux overnight. The reaction was detected by thin plate chromatography, and after the reaction was completed, it was cooled to room temperature, and the reaction was quenched with water. Extract 4×20 mL with ethyl acetate and wash with saturated brine. Dry over anhydrous sodium sulfate and remove sodium sulfate by filtration. The solvent was evaporated under reduced pressure to give a crude material. Using petroleum ether/ethyl acetate as the eluent, Purified by column chromatography (mobile phase: ethyl acetate / petroleum ether = 1/2) A pale yellow solid product was obtained in a yield of 61%.
 

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