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Chemical Structure| 782493-96-3 Chemical Structure| 782493-96-3

Structure of 782493-96-3

Chemical Structure| 782493-96-3

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Product Details of [ 782493-96-3 ]

CAS No. :782493-96-3
Formula : C11H17N3O2
M.W : 223.27
SMILES Code : O=C(C1=CN(C2CCNCC2)N=C1)OCC
MDL No. :MFCD20528138

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Application In Synthesis of [ 782493-96-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 782493-96-3 ]

[ 782493-96-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 345637-71-0 ]
  • [ 782493-96-3 ]
  • [ 922516-62-9 ]
YieldReaction ConditionsOperation in experiment
Step B: Preparation of ethyl 1-[1-[[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-4-piperidinyl]-1H-pyrazole-4-carboxylate. By a procedure analogous to that of Example 32 Step B, 1,1-dimethylethyl 4-[4-(ethoxycarbonyl)-1H-pyrazol-1-yl]-1-piperidinecarboxylate (0.38 g, 1.2 mmol) (i.e. the product of Example 33, Step A) was deprotected with trifluoroacetic acid (4 mL) to afford the corresponding amine (0.18 g). This amine was reacted with the acid chloride formed from <strong>[345637-71-0]5-methyl-3-(trifluoromethyl)-1H-pyrazole-1-acetic acid</strong> (0.18 g, 0.88 mmol) and oxalyl chloride (0.10 mL, 1.15 mmol) in the presence of triethylamine (0.16 mL, 1.15 mmol) to afford 0.24 g of the title compound as a white solid.1H NMR (CDCl3) 6 1.35 (t, 3H), 1.95 (m, 2H), 2.24 (m, 2H), 2.34 (s, 3H), 2.90 (m, IH), 3.32 (m, IH), 4.13 (m, IH), 4.30 (q, 2H), 4.37 (m, IH), 4.63 (m, IH), 4.99 (s, 2H), 6.34 (s, IH), 7.91 (s, IH), 7.92 (s, IH).
 

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