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Chemical Structure| 773887-07-3 Chemical Structure| 773887-07-3

Structure of 773887-07-3

Chemical Structure| 773887-07-3

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Product Details of [ 773887-07-3 ]

CAS No. :773887-07-3
Formula : C10H14BrN
M.W : 228.13
SMILES Code : NC1=C(C)C=C(Br)C=C1C(C)C
MDL No. :MFCD12547785

Safety of [ 773887-07-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 773887-07-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 773887-07-3 ]

[ 773887-07-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 773887-07-3 ]
  • [ 773887-09-5 ]
YieldReaction ConditionsOperation in experiment
58.1% With acetic acid; sodium nitrite; In water; Compound 15b (1.1 g, 4.8 mmol) was dissolved in 15 mL of acetic acid, and 2 mL of sodium nitrite (400 mg,Aqueous solution of 5.8 mmol) was stirred overnight. After the reaction solution is concentrated, a saturated sodium hydrogencarbonate solution is added.Ethyl acetate (20 mL × 3) was extracted, and the organic phase was combined, washed with saturated sodium chloride and dried over sodium sulfate.Concentrated under reduced pressure,The residue was purified by eluent system B using a CombiFlash rapid preparation apparatus.The title product 15c (670 mg, yield: 58.1%) was obtained.
 

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