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Chemical Structure| 771581-15-8 Chemical Structure| 771581-15-8

Structure of 771581-15-8

Chemical Structure| 771581-15-8

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Product Details of [ 771581-15-8 ]

CAS No. :771581-15-8
Formula : C5H6ClN3
M.W : 143.57
SMILES Code : NCC1=NC=CN=C1Cl
MDL No. :MFCD04038434

Safety of [ 771581-15-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P280-P305+P351+P338-P310

Application In Synthesis of [ 771581-15-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 771581-15-8 ]

[ 771581-15-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 771581-15-8 ]
  • [ 63845-28-3 ]
  • benzyl 4-(2-((3-chloropyrazin-2-yl)methylamino)-2-oxoethyl)piperidine-1-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
General procedure: R1-acid (1.0 eq), EDCI (1.5 eq), HOBt (1.0 eq) were taken in dry DCM, stirred at 0 oC for10 min, followed by addition of (3-chloropyrazin-2-yl)methanamine (1 eq.), the reaction wasstirred at room temperature for 3-6 h. Upon completion (monitored by thin layerchromatography), the reaction was extracted into DCM and washed with water, NaHCO3, andbrine. The organic layer was dried over Na2SO4, filtered, and concentrated in vacuo. The crudeproduct was then purified via flash chromatography over silica, eluting with a hexanes/EtOAcgradient.
 

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[ 771581-15-8 ]

Chemical Structure| 939412-86-9

A239564 [939412-86-9]

(3-Chloropyrazin-2-yl)methanamine hydrochloride

Reason: Free-salt