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Chemical Structure| 7462-76-2 Chemical Structure| 7462-76-2

Structure of 7462-76-2

Chemical Structure| 7462-76-2

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Product Details of [ 7462-76-2 ]

CAS No. :7462-76-2
Formula : C8H8ClNO
M.W : 169.61
SMILES Code : O=C(N)C(Cl)C1=CC=CC=C1
MDL No. :MFCD06654371

Safety of [ 7462-76-2 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 7462-76-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7462-76-2 ]

[ 7462-76-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 87-65-0 ]
  • [ 527-60-6 ]
  • [ 7462-76-2 ]
  • [ 15307-93-4 ]
YieldReaction ConditionsOperation in experiment
90.75% With sodium hydroxide; In water; N,N-dimethyl-formamide; toluene; EXAMPLE 1 Preparation of N-phenyl 2,6-dichloroaniline 37.6 g of 2,4,6-trimethyl phenol and 11 g of sodium hydroxide were dissolved in 30 ml of water and mixed with 150 ml of toluene. The toluene recovered from heating was mixed with 139 ml of N,N-dimethylformamide to obtain a N,N-dimethylformamide solution. 40 g of 2,6-dichlorophenol was dissolved in 130 ml of toluene, followed by the addition of 9.8 g of sodium hydroxide in 20 ml of water, 41.5 g of N-phenyl chloroacetamide and 8.7 ml of N,N-dimethylformamide, and refluxed in a oil bath at 140°-150° C. for 15 h. The toluene was recovered from the reflux, and mixed with the above N,N-dimethylformamide solution and reacted for 3 h. Recovering N,N-dimethylformamide from the reacted mixture with distillation under reduced pressure (145°-150° C., 8 mm Hg) resulted in the formation of 53 g of N-phenyl 2,6-dichloroaniline and the product yield was 90.75percent.
 

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