Home Cart Sign in  
Chemical Structure| 742100-61-4 Chemical Structure| 742100-61-4

Structure of 742100-61-4

Chemical Structure| 742100-61-4

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 742100-61-4 ]

CAS No. :742100-61-4
Formula : C6H14ClN
M.W : 135.64
SMILES Code : Cl.CC1CNCC1C
MDL No. :MFCD20731157

Safety of [ 742100-61-4 ]

Application In Synthesis of [ 742100-61-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 742100-61-4 ]

[ 742100-61-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 742100-61-4 ]
  • [ 228251-24-9 ]
  • [ 742100-88-5 ]
YieldReaction ConditionsOperation in experiment
With sodium carbonate; In water; dimethyl sulfoxide; at 80℃; for 3h; Reference Example 164 A suspension of <strong>[228251-24-9]5-bromo-2-chloronicotinaldehyde</strong> (1.5 g), 3,4-dimethylpyrrolidine hydrochloride (1.85 g) and sodium carbonate (1.8 g) in DMSO (45 ml) and water (22.5 ml) was stirred for 3 hours at 80C under a nitrogen atmosphere. After returning to room temperature, water was added thereto and the mixture was extracted with ethyl acetate. The organic layer was washed with saturated brine, and dried over magnesium sulfate. The solvent was distilled off under reduced pressure, which was separated and purified by silica gel column chromatography (hexane: ethyl acetate = 19: 1 ? hexane: ethyl acetate = 4: 1). The resulting residue recrystallized from hexane-ethyl acetate to give 5-bromo-2-(3,4-dimethylpyrrolidin-1-yl)nicotinaldehyde (1.56 g) as yellow crystals. m.p. 98.5-99.5C. 1H-NMR (300 MHz, CDCl3) delta 0.98 (6H, d, J=6.6 Hz), 2.31-2.41 (2H, m), 3.22-3.28 (2H, m), 3.59-3.65 (2H, m), 8.00 (1H, d, J=2.4 Hz), 8.29 (1H, d, J=2.4 Hz), 9.95 (1H, s). Elementary analysis C12H15N2OBr, Calcd. C, 50.90; H, 5.34; N, 9.89: Found C, 50.93; H, 5.35; N, 9.82.
 

Historical Records

Categories