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Chemical Structure| 741286-41-9 Chemical Structure| 741286-41-9

Structure of 741286-41-9

Chemical Structure| 741286-41-9

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Product Details of [ 741286-41-9 ]

CAS No. :741286-41-9
Formula : C13H14O4
M.W : 234.25
SMILES Code : O=C(OCC)C(CC(C1=CC=CC(C)=C1)=O)=O
MDL No. :MFCD11046242

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Application In Synthesis of [ 741286-41-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 741286-41-9 ]

[ 741286-41-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 179543-88-5 ]
  • [ 741286-41-9 ]
  • [ 741291-47-4 ]
YieldReaction ConditionsOperation in experiment
62% With triethylamine; In ethanol; at 20℃; for 14h;Heating / reflux; 2) The title compound; 5-Hydrazino-2-methoxypyridine hydrochloride (0.380 g) obtained from Referential Example 1 and triethylamine (0.30 mL) were added to a solution of the above-obtained 4-(3-methylphenyl)-2,4-dioxobutanoic acid ethyl ester (1.014 g) dissolved in ethanol (20 mL) at room temperature. The resultant mixture was refluxed under heat for 14 hours, and then cooled in air. The solvent was evaporated under reduced pressure, and the residue was partitioned between chloroform and water. The aqueous layer was extracted with chloroform. The organic layer was washed with saturated brine and dried over sodium sulfate anhydrate, followed by filtration. The solvent was evaporated under reduced pressure, and the residue was subjected to silica gel column chromatography (hexane - ethyl acetate: 20%), to thereby give the title compound as an oily substance (0.451 g, 62%).1H-NMR (400MHz, CDCl3) delta: 1.42(3H,t,J=7.1Hz), 2.30(3H,s), 3.92(3H,s), 4.45(2H,q,J=7.1Hz), 6.68-6.76(1H,m), 6.92-7.25(4H,m), 7.02(1H,s), 7.53-7.61(1H,m), 8.08-8.15 (1H, m) . MS (FAB)m/z: 338(M+H)+.
  • 2
  • [ 741286-41-9 ]
  • [ 28710-97-6 ]
  • ethyl 3-oxo-2-phenyl-6-m-tolyl-2,3-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylate [ No CAS ]
 

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