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Chemical Structure| 7252-82-6 Chemical Structure| 7252-82-6

Structure of 7252-82-6

Chemical Structure| 7252-82-6

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Product Details of [ 7252-82-6 ]

CAS No. :7252-82-6
Formula : C10H14O2
M.W : 166.22
SMILES Code : OCCCC1=CC=CC(OC)=C1
MDL No. :MFCD00798002
InChI Key :XOBQNLCSYCFLQG-UHFFFAOYSA-N
Pubchem ID :96130

Safety of [ 7252-82-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 7252-82-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7252-82-6 ]

[ 7252-82-6 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 7252-82-6 ]
  • [ 6943-97-1 ]
YieldReaction ConditionsOperation in experiment
With N-Bromosuccinimide; triphenylphosphine; In dichloromethane; at 20℃; for 16h;Ice-cooling; (16-2) Synthesis of 1-(3-bromopropyl)-3-methoxybenzene (compound 16-2) Compound 16-1 (2.00 g) was dissolved in methylene chloride (50 ml), triphenylphosphine (3.58 g) and N-bromosuccinimide (2.40 g) were added under ice-cooling, and the mixture was stirred under ice-cooling for 1 hr, and further at room temperature for 15 hr. The reaction mixture was washed with water and saturated brine, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure. Diethyl ether (100 ml) was added, and the precipitated triphenylphosphine oxide was filtered off. The concentrate of the filtrate was purified by silica gel column chromatography (hexane alone) to give the object product (2.07 g) as a pale-yellow oil. 1H-NMR(CDCl3) delta (ppm): 2.13-2.20(2H, m), 2.76(2H, t, J=7.4Hz), 3.40(2H, t, J=6.6Hz), 3.80(3H, s), 6.74-6.70(3H, m), 7.18-7.23(1H, m).
  • 2
  • [ 7252-82-6 ]
  • [ 106-95-6 ]
  • [ 6943-97-1 ]
YieldReaction ConditionsOperation in experiment
With 1,1'-carbonyldiimidazole; In acetonitrile; Step B Preparation of 3-(3-Methoxyphenyl)propylbromide Allyl bromide (25 mL, 0.28 mmol) was added to a solution of 3-(3-methoxyphenyl)propanol (8.8 g, 0.053 mol), N,N'-carbonyldiimidazole (9.6 g, 0.0605 mol) and CH3CN (45 mL) at room temperature. After 1.5 hr at rt and 1.5 hr at reflux, the reaction mixture was cooled, partitioned between EtOAc (250 mL) and H2O (300 mL), the organic layer washed with H2O (300mL), 5% HCl (200 mL), dilute NaHCO3 solution (200 mL), brine (300 mL), and dried (Na2SO4). Filtration and concentration to dryness gave the title compound.
 

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