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Structure of 724726-05-0

Chemical Structure| 724726-05-0

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Product Details of [ 724726-05-0 ]

CAS No. :724726-05-0
Formula : C12H10ClN3O
M.W : 247.68
SMILES Code : O=C1C2=C(NC(C3=CC(Cl)=NC=C3)=C2)CCN1
MDL No. :MFCD22495382
InChI Key :JTRXEPCDEVNYPE-UHFFFAOYSA-N
Pubchem ID :16720432

Safety of [ 724726-05-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 724726-05-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 724726-05-0 ]

[ 724726-05-0 ] Synthesis Path-Downstream   1~1

  • 1
  • 2-bromo-1-(2-chloro-4-pyridinyl)-ethanone hydrobromide [ No CAS ]
  • [ 50607-30-2 ]
  • [ 724726-05-0 ]
YieldReaction ConditionsOperation in experiment
47.5% With ammonium acetate; In ethanol; at 20℃; for 2h; To a round bottom flask charged with 3A (6.06 g, 19.21 mmol), <strong>[50607-30-2]piperidine-2,4-dione</strong> (2.391 g, 21.14 mmol), ammonium acetate (5.92 g, 77 mmol) and ethanol (64.0 ml) were added. The reaction mixture was stirred at rt for 2 h. Water (20 ml) was added and stirring was continued for 3 h. The product was collected via filtration. The collected solid was washed with water and dried under vacuum ON, yielding 3B (2.26 g, 9.12mmol, 47.5percent yield) as a white solid. MS(ES+) m/z 248.0 (M+H).
 

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