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Chemical Structure| 722491-59-0 Chemical Structure| 722491-59-0

Structure of 722491-59-0

Chemical Structure| 722491-59-0

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Product Details of [ 722491-59-0 ]

CAS No. :722491-59-0
Formula : C8H12F4N2Si
M.W : 240.27
SMILES Code : C[Si](C(F)(F)C(N1C=CN=C1)(F)F)(C)C
MDL No. :MFCD04116438

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Application In Synthesis of [ 722491-59-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 722491-59-0 ]

[ 722491-59-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 722491-59-0 ]
  • [ 1391728-13-4 ]
  • 1-(2-(3,3-dimethyl-1λ3-benzo[d][1,2]iodaoxol-1(3H)-yl)-1,1,2,2-tetrafluoroethyl)-1H-imidazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
80% With tetrabutylammonium triphenyldifluorosilicate; In acetonitrile; at -35 - 0℃; for 1h; 1 equivalent of 1-[(1,1,2,2-Tetrafluoro-2-trimethylsilyl)ethyl]-lH-imidazole was treated with 2 equivalents of fluoroiodane alcohol in the presence of 1 mol% TBAT in acetonitrile at a temperature of -35C to 0C for 1 hour providing Im-I in 77-80% isolated yield. Similarly as in the case of synthesis of PhS-I, the Um- polung of 1-[(1,1,2,2-Tetrafluoro-2-trimethylsilyl)ethyl]-lH-imidazole with fluoroiodane alcohol was essentially finished within 10 minutes after addition of silane was complete (as evidenced by TLC analysis). Reagent Im-I was obtained as a viscous yellowish liquid that soon crystallized at ambient temperature (20C to 25C) .
 

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