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Chemical Structure| 71605-72-6 Chemical Structure| 71605-72-6

Structure of 71605-72-6

Chemical Structure| 71605-72-6

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Product Details of [ 71605-72-6 ]

CAS No. :71605-72-6
Formula : C7H4N2OS
M.W : 164.18
SMILES Code : O=CC1=CC2=NSN=C2C=C1
MDL No. :MFCD00457949
InChI Key :GEFIFDVQYCPLHC-UHFFFAOYSA-N
Pubchem ID :2776290

Safety of [ 71605-72-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 71605-72-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 71605-72-6 ]

[ 71605-72-6 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 17115-51-4 ]
  • [ 5220-49-5 ]
  • [ 71605-72-6 ]
  • [ 315187-64-5 ]
  • 2
  • [ 21080-80-8 ]
  • [ 934-22-5 ]
  • [ 71605-72-6 ]
  • [ 1024609-37-7 ]
YieldReaction ConditionsOperation in experiment
16% Compound 287: 1 -(1 H-Benzoimidazol-5-yl)-5-benzo[c][1 ,2,5]thiadiazol-5-yl-4- cyclopropanecarbonyl-S-hydroxy-I .S-dihydro-pyrrol^-one; 1 H-Benzoimidazol-5-ylamine (1 mmol) and Benzo[1 ,2,5]thiadiazole-5-carbaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 4-Cyclopropyl-2,4-dioxo-butyric acid ethyl ester (1 mmol) was added. The reaction was heated to 500C and stirred for 24h. After evaporation of the solvent the residue was purified with chromatographic methods.molecular weight (g/mol): 417.45 IC50 hQC (nM): 0.7Yield: 0.05 g (16 percent); mp: 270.000C, decomposed, 1H NMR delta 1 H-NMR (500 MHz, DMSO-D6): 0.66-0.71 (m, 1 H, CH2), 0.77-0.84 (m, 2 H, CH2), 0.89-0.95 (m, 1 H, CH2), 2.91-2.95 (CH-CH2), 6.36 (s, 1 H, CH-N), 7.45-7.50 (m, 3 H, Ar), 7.85-7.87 (m, 2 H, Benzimid), 8.12 (d, 4J=0.9 Hz, 1 H, Benzimid), 9.03 (s, 1 H, Benzimid). MS m/z 418.4 (M+H)+, HPLC (254 nm): rt 2.74 min (100 percent).
 

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