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Chemical Structure| 7145-28-0 Chemical Structure| 7145-28-0

Structure of 7145-28-0

Chemical Structure| 7145-28-0

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Product Details of [ 7145-28-0 ]

CAS No. :7145-28-0
Formula : C7H8N2O2
M.W : 152.15
SMILES Code : O=C(N)C1=C(OC)N=CC=C1
MDL No. :MFCD08704236

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Application In Synthesis of [ 7145-28-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7145-28-0 ]

[ 7145-28-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 7145-28-0 ]
  • [ 75-65-0 ]
  • [ 161117-83-5 ]
YieldReaction ConditionsOperation in experiment
With lead(IV) tetraacetate; for 2h;Inert atmosphere; Reflux; To a suspension of 2- methoxynicotinamide (87; 10 mmol) in anhydrous tert-butyl alcohol (25 mL) is added lead tetraacetate (4.44 g, 10 mmol) under nitrogen atmosphere. The reaction mixture is heated to reflux for 2 h, then cooled and filtered through diatomaceous earth. The filtrate is concentrated and the residue dissolved in diethyl ether. The solution is washed with saturated aqueous sodium bicarbonate and brine, then dried with sodium sulfate, filtered, and concentrated to give the desired product 88 which can be purified by recrystallization.
 

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