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Chemical Structure| 7064-38-2 Chemical Structure| 7064-38-2

Structure of 7064-38-2

Chemical Structure| 7064-38-2

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Product Details of [ 7064-38-2 ]

CAS No. :7064-38-2
Formula : C4H4INO
M.W : 208.99
SMILES Code : CC1=C(I)C=NO1
MDL No. :MFCD06411541
InChI Key :NFLDXKDDDKVRSN-UHFFFAOYSA-N
Pubchem ID :2795461

Safety of [ 7064-38-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P264-P302+P352-P304+P340-P305+P351+P338-P332+P313-P337+P313

Application In Synthesis of [ 7064-38-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7064-38-2 ]

[ 7064-38-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 219735-99-6 ]
  • [ 7064-38-2 ]
  • 4-(2-chloro-4-methoxyphenyl)-5-methylisoxazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
With sodium hydrogencarbonate;tetrakis(triphenylphosphine) palladium(0); In 1,2-dimethoxyethane; water; at 80℃; for 16h; Reference example 4 4-(2-chloro-4-methoxyphenyl)-5-methylisoxazole To a suspension of the compound prepared in reference example 3 (644 mg), 4-iodo-5-methylisoxazole (658 mg) and sodium bicarbonate (791 mg) in dimethoxyethane (2.5 ml) / water (2.5 ml), tetrakis (triphenylphosphine) palladium (36 mg) was added. The mixture was stirred for 16 hours at 80§C. To the reaction mixture that was cooled to room temperature, water and ethyl acetate were added. An insoluble matter was removed by filtration. An organic layer was separated from filtrate, it was washed with a saturated aqueous solution of sodium chloride, dried over anhydrous sodium sulfate and concentrated. The residue was purified by column chromatography on silica gel (n-hexane: ethyl acetate = 19: 1 ? 15: 1) to give the title compound (637 m g) having the following physical data. TLC: Rf 0.44 (n-hexane: ethyl acetate = 3: 1); NMR (300MHz, CDCl3): delta 8.29 (brs, 1H), 7.16 (d, J = 8.4Hz, 1H), 7.04 (d, J = 2.4Hz, 1H), 6.87 (dd, J = 8.4, 2.4Hz, 1H), 3.84 (s, 3H), 2.41 (brs, 3H).
  • 2
  • [ 503184-35-8 ]
  • [ 7064-38-2 ]
  • C11H12N2O2 [ No CAS ]
 

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