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Chemical Structure| 698367-00-9 Chemical Structure| 698367-00-9

Structure of 698367-00-9

Chemical Structure| 698367-00-9

5-(Chloromethyl)-3-methyl-1-phenyl-1H-pyrazole-4-carbonitrile

CAS No.: 698367-00-9

4.5 *For Research Use Only !

Cat. No.: A1040196 Purity: 95%

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Product Details of [ 698367-00-9 ]

CAS No. :698367-00-9
Formula : C12H10ClN3
M.W : 231.68
SMILES Code : N#CC1=C(CCl)N(C2=CC=CC=C2)N=C1C
MDL No. :MFCD07329919

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Application In Synthesis of [ 698367-00-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 698367-00-9 ]

[ 698367-00-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 698367-00-9 ]
  • [ 18299-15-5 ]
  • 5-[[4-(hydroxymethyl)-2-methylphenoxy]methyl]-3-methyl-1-phenyl-1H-pyrazole-4-carbonitrile [ No CAS ]
YieldReaction ConditionsOperation in experiment
61% With caesium carbonate; at 80℃; for 4h; General procedure: A mixture of the chloride 4 (1.0 eq), the appropriate alcohol (1.0 eq), and K2CCh or Cs2C03 (2.0 eq) in acetonitrile or A, A- d i m c t h y 1 fo r m a m i d c was stirred for a time period between 2h and overnight at a temperature ranging between room temperature and the reflux temperature. After cooling to rt, H20 was added and the reaction mixture was extracted with EtOAc (x3). The combined organic layers were washed with brine, dried over Na2S04, filtered and evaporated under vacuum. The desired product was obtained after purification of the crude material as reported in the specific examples.
 

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