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Chemical Structure| 697738-97-9 Chemical Structure| 697738-97-9

Structure of 697738-97-9

Chemical Structure| 697738-97-9

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Product Details of [ 697738-97-9 ]

CAS No. :697738-97-9
Formula : C10H8N2O3
M.W : 204.18
SMILES Code : O=C1N(C2=C(C=C1)C([N+]([O-])=O)=CC=C2)C
MDL No. :MFCD27927541

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Application In Synthesis of [ 697738-97-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 697738-97-9 ]

[ 697738-97-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 697738-97-9 ]
  • [ 59-31-4 ]
  • [ 13067-94-2 ]
YieldReaction ConditionsOperation in experiment
34% With trichlorophosphate; In 1,2-dichloro-benzene; 5(iii) 2-Chloro-5-nitroquinoline (10) Phosphorous oxychloride (25 mL) was added slowly to a solution of carbostyril 9 (1.5 g, 7.35 mmol) in o-dichlorobenzene at 0 C. and then refluxed for 12 h. The reaction mixture was then quenched by pouring into the ice-cold water and then extracted with chloroform. Solvent was then dried over anhydrous sodium sulphate, filtered and evaporated to obtain a gummy residue. The product was obtained as a light brown solid by trituration with water (520 mg, 34% yield). 1H-NMR (300 MHz, CDCl3) delta=9.02 (1H, d, J=9 Hz, Ar-H), 8.43 (1H, d, J=9 Hz, Ar-H), 8.36 (1H, d, J=9 Hz, Ar-H), 7.87 (1H, t, J=9 Hz, Ar-H, 7.66 (1H, d, J=9 Hz, Ar-H). LCMS Mass Found=[M+H)+ 209, Calcd for C9H5N2O2Cl 208.
 

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