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Chemical Structure| 69316-09-2 Chemical Structure| 69316-09-2

Structure of 69316-09-2

Chemical Structure| 69316-09-2

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Product Details of [ 69316-09-2 ]

CAS No. :69316-09-2
Formula : C9H5Cl2NO
M.W : 214.05
SMILES Code : N#CCC(C1=CC(Cl)=CC(Cl)=C1)=O
MDL No. :MFCD00662057
InChI Key :HRKMSEMFAARJCZ-UHFFFAOYSA-N
Pubchem ID :2758064

Safety of [ 69316-09-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H312-H315-H319-H332-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 69316-09-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 69316-09-2 ]

[ 69316-09-2 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 69316-09-2 ]
  • [ 2243-58-5 ]
  • [ 907190-89-0 ]
YieldReaction ConditionsOperation in experiment
The mixture of <strong>[2243-58-5]2-naphthylhydrazine hydrochloride</strong> (1.81g, 9.33mmol), 3-(3,5-dichlorophenyl)-3- oxopropanenitrile (2.44g, 11.45mmol) in 50ml toluene was heated to 13O0C for 12 hours. The reaction mixture was quenched with aqueous sodium bicarbonate (10OmL), extracted with EtOAc (3 x 10OmL) and the combined organic extracts washed with brine. The organic phase was dried over Na2SC^ and concentrated in vacuo. The crude purified by liquid chromatography on silica gel using an ISCO single channel system (Etaexane/EtOAc: 10/0 to 1/9) to give 3-(3,5-dichlorophenyl)-l-(2-naphthyl)-lH-pyrazol- 5-amine as product. 1H NMR (CD3Cl3, 500 MHz) delta 8.055-8.051 (d, IH), 8.00-7.98 (d, IH), 7.90-7.88 EPO <DP n="42"/>(m, 2H), 7.78-7.60 (dd, IH), 7.726-7.722 (m, 2H), 7.57-7.53 (m, 2H), 7.29-7.28 (t, IH), 5.96 (s, IH), 3.95 (s, 2H). MS (ESI) 353.97 (M+-I-H).
  • 2
  • [ 18293-53-3 ]
  • [ 3032-81-3 ]
  • [ 13939-06-5 ]
  • [ 69316-09-2 ]
  • 3
  • [ 3032-81-3 ]
  • [ 69316-09-2 ]
 

Historical Records

Technical Information

• Alkyl Halide Occurrence • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Benzylic Oxidation • Birch Reduction • Blaise Reaction • Blanc Chloromethylation • Bucherer-Bergs Reaction • Catalytic Hydrogenation • Clemmensen Reduction • Complex Metal Hydride Reductions • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Fischer Indole Synthesis • Friedel-Crafts Reaction • General Reactivity • Grignard Reaction • Henry Nitroaldol Reaction • Hiyama Cross-Coupling Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Hydrogenolysis of Benzyl Ether • Kinetics of Alkyl Halides • Kumada Cross-Coupling Reaction • Lawesson's Reagent • Leuckart-Wallach Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Alkylbenzene • Preparation of Amines • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Alkyl Halides with Reducing Metals • Reactions of Amines • Reactions of Benzene and Substituted Benzenes • Reformatsky Reaction • Ritter Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Ketenes • Stille Coupling • Stobbe Condensation • Substitution and Elimination Reactions of Alkyl Halides • Suzuki Coupling • Tebbe Olefination • Thorpe-Ziegler Reaction • Ugi Reaction • Vilsmeier-Haack Reaction • Wittig Reaction • Wolff-Kishner Reduction

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