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Chemical Structure| 676270-67-0 Chemical Structure| 676270-67-0

Structure of 676270-67-0

Chemical Structure| 676270-67-0

N-((1R,2R)-2-Amino-1,2-diphenylethyl)-1-(7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonamide

CAS No.: 676270-67-0

4.5 *For Research Use Only !

Cat. No.: A103649 Purity: 97%

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Product Details of [ 676270-67-0 ]

CAS No. :676270-67-0
Formula : C24H30N2O3S
M.W : 426.57
SMILES Code : O=S(CC1(C2(C)C)C(CC2CC1)=O)(N[C@H](C3=CC=CC=C3)[C@H](N)C4=CC=CC=C4)=O
MDL No. :MFCD29035126

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Application In Synthesis of [ 676270-67-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 676270-67-0 ]

[ 676270-67-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 35132-20-8 ]
  • [ 21286-54-4 ]
  • [ 676270-67-0 ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In dichloromethane; at 0 - 20℃; for 5h; General procedure: To a stirred solution of triethylamine (1.39 mL, 10 mmol) and (1S,2S)-1,2-diphenylethane-1,2-diamine (1.06 g, 5 mmol) in CH2Cl2 (15 mL) at 0 C, (1S)-(+)-10-camphorsulfonyl chloride 1 (1.25 g, 5 mmol) in CH2Cl2 (5 mL) was added dropwise. Then after stirring at the same temperature for 1 h, and then at room temperature for another 4 h, the reaction mixture was quenched with water and extracted with CH2Cl2. The organic phase was separated and dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure. The residue was purified by crystallization with ethyl acetate and methanol to afford (S,S,S)-CsDPEN as a white solid (1.04 g, 48% yield).
 

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