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Chemical Structure| 67455-41-8 Chemical Structure| 67455-41-8

Structure of 67455-41-8

Chemical Structure| 67455-41-8

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Product Details of [ 67455-41-8 ]

CAS No. :67455-41-8
Formula : C10H15N3
M.W : 177.25
SMILES Code : NC1=CC=C(C=C1)N1CCNCC1
MDL No. :MFCD01365906
InChI Key :VAVOYRCCWLRTMS-UHFFFAOYSA-N
Pubchem ID :422925

Safety of [ 67455-41-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 67455-41-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 67455-41-8 ]

[ 67455-41-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 67455-41-8 ]
  • [ 73183-34-3 ]
  • [ 912369-50-7 ]
YieldReaction ConditionsOperation in experiment
68% General procedure: To a solution of arylamine (0.5 mmol, 1.0 equiv) in MeOH(1.0 mL) was added HCl (0.5 mL, 1.5 mmol, 3.0 equiv) followed by H2O (0.5 ml). This mixture was stirred 2 min, and the NaNO2 solution (0.25 mL) was then added. The NaNO2 solution was prepared by dissolving 35 mg of NaNO2 in H2O (0.25 mL). This mixture was stirred 30 minat 0-5 C followed by B2pin2 (2, 381 mg, 1.5 mmol, 3.0equiv) in MeOH (1.0 mL). This mixture was stirred 60 min.H2O (10 mL) was added to the reaction mixture, then extracted with CH2Cl2 (50 mL, 3×). The combined organic layers were washed with sat. NaHCO3, dried over Na2SO4, followed by evaporation, and the crude residue was purified by flash chromatography.
 

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