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Structure of 6575-07-1

Chemical Structure| 6575-07-1

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Product Details of [ 6575-07-1 ]

CAS No. :6575-07-1
Formula : C7H3ClN2O2
M.W : 182.56
SMILES Code : [O-][N+](=O)C1=CC=CC(Cl)=C1C#N
MDL No. :MFCD00007203
InChI Key :ZHLCARBDIRRRHD-UHFFFAOYSA-N
Pubchem ID :81053

Safety of [ 6575-07-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302+H312+H332-H315-H319-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 6575-07-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6575-07-1 ]

[ 6575-07-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 6575-07-1 ]
  • [ 101252-73-7 ]
YieldReaction ConditionsOperation in experiment
(a) Preparation of (2-chloro-6-nitrophenyl)methylamine.To a cooled (0 C.) solution of 1M BH3.THF (Fluka) (100 ML, 100 mmol) was added 5-chloro-2-nitrobenzonitrile (3.69 g, 20 mmol) in three portions.After complete addition, the reaction was warmed to RT. After 15 h, the solvent was concentrated to one-half its original volume.The concentrated solution was carefully added to 10% HCl (100 ML) and heated to reflux.After 2.5 h, the solution was cooled to RT and the volatiles were removed in vacuo.The aqueous solution was basified with 1N NaOH and extracted with CH2Cl2.The combined organics were dried over Na2SO4 and concentrated in vacuo to afford a red oil. MS m/z: 187 (M+1). Calc'd for C7H7ClN2O2-186.02.
 

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