Alternatived Products of [ 6386-24-9 ] Product Details of [ 6386-24-9 ]
CAS No. : | 6386-24-9 | MDL No. : | MFCD00132927 |
Formula : |
C34H36O6 | Boiling Point : | - |
Linear Structure Formula : | C6H7O2(OCH2C6H5)4H | InChI Key : | OGOMAWHSXRDAKZ-BJPULKCASA-N |
M.W : |
540.65
| Pubchem ID : | 2734154 |
Synonyms : | |
Application In Synthesis of [ 6386-24-9 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 6386-24-9 ]
- 1
- [ 6386-24-9 ]
- [ 84500-41-4 ]
- [ 77943-01-2 ]
- [ 77943-00-1 ]
- 2
- [ 6386-24-9 ]
- [ 73724-48-8 ]
- [ 86117-97-7 ]
- [ 86088-46-2 ]
- 3
- [ 48149-72-0 ]
- [ 6386-24-9 ]
- 4
- [ 6386-24-9 ]
- [ 122194-07-4 ]
- 2,3,4,6-tetra-O-benzyl-D-galactopyranosyl dimethyl phosphite [ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
| | 1H-Tetrazole (0.48 g, 6.8 mmol) was added to a solution of the reducingsugar S3 (3.1 g, 5.7 mmol) and i-Pr2NP(OMe)2 (1.6mL, 6.8 mmol) in dry CH2Cl2 (25 mL) at 0 C. The mixturewas stirred for 5 min and warmed to rt. After being stirred for 5 min, i-Pr2NP(OMe)2 (0.10mL, 0.43 mmol) was added to the solution. The reaction was quenched with asaturated NaHCO3 aqueous solution (40 mL) after 30 min. The mixturewas extracted with CH2Cl2 (200 mL) and the organic layerwas washed with saturated NaHCO3 aqueous solutions (3 × 200 mL). Theaqueous layer was then back-extracted with CH2Cl2 (200 mL).The combined organic layers were dried over Na2SO4,filtered and concentrated under reduced pressure. The residue was dissolved in freshlydistilled THF (23 mL) and a solution of BH3?THF (0.99 M, 17 mL, 17mmol) in THF was added to the solution at 0 C. The reaction mixture wasstirred for 5 min and warmed to rt. After being stirred for 12 h, the mixturewas concentrated under reduced pressure. The residue was dissolved in CHCl3(150 mL) and successively washed with saturated NaHCO3 aqueoussolutions (2 × 150 mL) and a brine (150 mL). The aqueous layer wasback-extracted with CHCl3 (150 mL). The combined organic layers weredried over Na2SO4, filterd and concentrated under reducedpressure. Purification of the residue by silica gel column chromatography[hexane-AcOEt (7:1, v/v)] gave 7 as a colorless syrup (3.5 g, 5.4mmol, 97%, a/b = 67:33). The 1H and 31PNMR spectra were in good agrrement with the reported data.1 |