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Chemical Structure| 631911-09-6 Chemical Structure| 631911-09-6

Structure of 631911-09-6

Chemical Structure| 631911-09-6

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Product Details of [ 631911-09-6 ]

CAS No. :631911-09-6
Formula : C14H20BNO3
M.W : 261.12
SMILES Code : O=C(N)C1=CC=C(B2OC(C)(C)C(C)(C)O2)C(C)=C1
MDL No. :MFCD18732747

Safety of [ 631911-09-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H312-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 631911-09-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 631911-09-6 ]

[ 631911-09-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 73183-34-3 ]
  • [ 170229-98-8 ]
  • [ 631911-09-6 ]
YieldReaction ConditionsOperation in experiment
71% With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 100℃; for 3h;Sealed tube; Inert atmosphere; To a sealed tube was added 4-bromo-3-methyl-benzamide (1.0 g, 4.67 mmol), bis(pinacolato)diboron (1.4 g, 5.61 mol), potassium acetate (1.4 g, 14.01 mmol), Pd(dppf)Cl2 (341 mg, 0.47 mmol) and 1,4-dioxane (10 mL). The mixture was bubbled through with N2 for 2 minutes and stirred at 100 C. for 3 hours. The mixture was concentrated in vacuo and purified by silica gel chromatography (petroleum ether/ethyl acetate, 1:1 to 0:100) to afford 3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (920 mg, 71% yield) as a white solid. LCMS (ESI) [M+H]+=262.2.
 

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