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Chemical Structure| 62882-10-4 Chemical Structure| 62882-10-4

Structure of 62882-10-4

Chemical Structure| 62882-10-4

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Product Details of [ 62882-10-4 ]

CAS No. :62882-10-4
Formula : C9H8N2O
M.W : 160.17
SMILES Code : NC1=CC=CC=C1C2=NC=CO2
MDL No. :MFCD14657169

Safety of [ 62882-10-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Application In Synthesis of [ 62882-10-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 62882-10-4 ]

[ 62882-10-4 ] Synthesis Path-Downstream   1~2

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  • [ 62882-10-4 ]
  • [ 92346-48-0 ]
  • 2
  • [ 615-43-0 ]
  • [ 145214-05-7 ]
  • [ 62882-10-4 ]
YieldReaction ConditionsOperation in experiment
80% tetrakis(triphenylphosphine) palladium(0); In 1,4-dioxane; at 95℃; for 2h;Heating / reflux; To a solution of 2-iodoaniline (1. 0 g, 4. 56 mol) in 1, 4-DIOXANE (18 ml) is added Pd (Ph3P) 4 (0.527 g, 0.456 mmol) and 2- (TRIBUTYLSTANNYL)-1, 3-oxazole (17.8 g, 49.7 mmol). The reaction mixture is purged with argon and refluxed at 95oC for 2hr. The mixture is concentrated, diluted with N-HEXANES, extracted with CH3CN, and concentrated under vacuum. The residue is purified by silica gel chromatography (CHZCLZ) to afford 2- (1, 3-oxazol-2-yl) aniline as a brown solid 0.587 g (80%). MS (ESI+) for C9H8N20 NALZ 161. 1 (M+H) +.
 

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