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Chemical Structure| 62146-62-7 Chemical Structure| 62146-62-7
Chemical Structure| 62146-62-7

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CAS No. :62146-62-7
Formula : C12H18N2O2
M.W : 222.28
SMILES Code : O=C(OCC1=CC=CC=C1)NCCCCN
MDL No. :MFCD02094512

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GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362

Application In Synthesis

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 62146-62-7 ]

[ 62146-62-7 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 62146-62-7 ]
  • [ 156866-52-3 ]
  • [ 675138-10-0 ]
YieldReaction ConditionsOperation in experiment
The compound (951.6 mg) obtained in Example 103-3 was dissolved in anhydrous methanol (38 ml) and added with (4-amino-butyl)-carbamic acid benzyl ester (898.0 mg) and trimethyl orthoformate (1.33 ml), followed by stirring at room temperature for 15.5 hours. After that, the solution was cooled with ice and added with sodium borohydride (458.5 mg), followed by stirring at room temperature for 1.5 hours. After the reaction, the solvent was distilled off and the residue was then added with water, followed by extraction with chloroform. The extract was washed with saturated saline solution and dried with anhydrous magnesium sulfate. The solvent was distilled off and the residue was then purified through silica gel column chromatography (chloroform/ethyl acetate), thereby obtaining the subject compound (1.1479 g) as a colorless oily substance. MS(FAB,Pos.):m/z=442[M+H]+
 

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