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Chemical Structure| 6205-69-2 Chemical Structure| 6205-69-2

Structure of 6205-69-2

Chemical Structure| 6205-69-2

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Product Details of [ 6205-69-2 ]

CAS No. :6205-69-2
Formula : C14H20N4O8
M.W : 372.33
SMILES Code : O=C(OC[C@@H]1[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](NC(C)=O)[C@H](N=[N+]=[N-])O1)C
MDL No. :MFCD00216968

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Application In Synthesis of [ 6205-69-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6205-69-2 ]

[ 6205-69-2 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 98045-03-5 ]
  • [ 6205-69-2 ]
  • [ 98045-02-4 ]
  • 2
  • [ 6205-69-2 ]
  • [ 37972-24-0 ]
  • [ 1312592-24-7 ]
YieldReaction ConditionsOperation in experiment
With copper(II) sulfate; sodium L-ascorbate; In tetrahydrofuran; water; tert-butyl alcohol; at 20℃; To a stirred solution of alkyne precursor 8b-16b (1.2 equiv) in THF was added dropwise a 1.0 M solution of TBAF in THF (1.44 equiv). The reaction mixture was stirred at room temperature for about 15 min. TLC analysis showed complete conversion of starting material to a major product (the de-silylation intermediate was slightly more polar than the alkyne precursor). The glycosyl azide (1.0 equiv), and 1:1 tert-butyl alcohol-water were then added to the above solution. A solution of sodium ascorbate (0.4 equiv) in water, followed by CuSO4 (0.2 equiv) in water, was successively added. The bright-yellow suspension was stirred vigorously at room temperature overnight. TLC analysis showed complete conversion of the starting material to a major product. The mixture was evaporated under reduced pressure, and the resultant residue was purified by flash chromatography to yield pure material.
  • 3
  • [ 6205-69-2 ]
  • [ 37972-24-0 ]
  • [ 1312592-07-6 ]
 

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