*Storage: {[sel_prStorage]}
*Shipping: {[sel_prShipping]}
The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
4.5
*For Research Use Only !
Change View
Size | Price | VIP Price | US Stock |
Global Stock |
In Stock | ||
{[ item.pr_size ]} |
Inquiry
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price, item.discount_usd) ]} {[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]} |
Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]} | Inquiry {[ item.pr_usastock ]} In Stock Inquiry - | {[ item.pr_chinastock ]} {[ item.pr_remark ]} In Stock 1-2 weeks - Inquiry - | Login | - + | Inquiry |
Please Login or Create an Account to: See VIP prices and availability
US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days
1-2weeks
Inquiry
{[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
{[ getRatePrice(item.pr_usd,1,item.mem_rate,item.pr_is_large_size_no_price, item.pr_usd) ]}
Inquiry
{[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price, item.vip_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
In Stock
- +
Please Login or Create an Account to: See VIP prices and availability
US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
CAS No. : | 619-60-3 |
Formula : | C8H11NO |
M.W : | 137.18 |
SMILES Code : | CN(C)C1=CC=C(O)C=C1 |
MDL No. : | MFCD01707548 |
InChI Key : | JVVRCYWZTJLJSG-UHFFFAOYSA-N |
Pubchem ID : | 22174 |
GHS Pictogram: |
![]() |
Signal Word: | Warning |
Hazard Statements: | H302-H315-H319-H332-H335 |
Precautionary Statements: | P261-P280-P305+P351+P338 |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
81% | The second step, 28.2 grams of oil,200 ml of toluene,27 grams of anhydrous aluminum chloride was added to a 500 ml three-neck bottle.The temperature was refluxed for 6 hours in an oil bath.Cool down to 80 ° C,Slowly add 100 ml of saturated sodium bicarbonate solution.Produce a solid,Continue to stir for 10 minutes.Filter out the insoluble matter while hot,After filtration, hot liquid separation,Add 50 ml of water to the toluene.Warmed up to 80 ° C together,Stir for 10 minutes,Liquid separation,The toluene phase is dried,Then use an oil pump to decompress and distill.Curing to obtain 20.8 grams of product,99.8percent purity,The yield was 81percent. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With triethylamine; phosphorus trichloride; In toluene; at 0 - 20℃; for 0.5h; | Example 4: Synthesis of tris(4-(dimethylamino)phenyl) phosphite (TDAPP), a palladium-binding ligand Step 2: Preparation of tris(4-(dimethylamino)phenyl) phosphite (TDAPP) Et3N (39.03 mL, 280 mmol, 1.40 equiv) was charged to the reaction mixture obtained in step 1. The batch temperature was adjusted to 2 °C (0 to 5 °C). A solution of PC13 (7.00 mL, 80 mmol, 0.40 equiv) in toluene (43.2 mL, 2 vol) was slowly charged to the reactor while maintaining the reaction temperature < 12 °C. The reaction is exothermic and the mixture becomes thick. Vigorous stirring was required for efficient mixing. The batch was agitated for 30 minutes at 15 °C (10 to 20 °C). An aliquot of the reaction was withdrawn for HPLC analysis. The reaction is deemed complete when the amount of DAP is < 2percent with respect to TDAPP. TBME (174.4 mL, 8 vol) was charged and the batch was agitated for 2 hours at 23 °C (20 to 25 °C) to ensure thorough precipitation of the Et3N HCl from the solution. The batch was filtered through a pad of celite (21.8 g, 1 wt. equiv)/silica gel (10.8 g, 0.5 wt. equiv). The pad of celite/silica gel was washed with TBME (43.2 mL, 2 vol). Precipitation of white crystals (Et3N*HCl salt) may form in the filtrate. If precipitation occurs, the filtrate should be filtered through a pad of celite/silica gel. The batch was concentrated under reduced pressure to 3 volumes (65.4 mL) at 43 °C (40 to 45 °C). 2-Methyl-2-butanol (174.4 mL, 8 vol) was charged to the batch. A precipitate may form during addition of the alcohol. The batch was then concentrated under reduced pressure to 6 vol (130.8 mL). Next, 2-methyl-2-butanol (43.2 mL, 2 vol) was charged to the batch. A thick slurry is formed after 2-methyl-2-butanol addition. An aliquot of the batch was removed to determine residual toluene content by GC-FID. The toluene content may affect the following crystallization. The batch temperature was adjusted to 63 °C (60 to 65 °C), resulting in a clear solution. The batch temperature was then adjusted to 40 - 45 °C and seeded with TDAPP seed crystals (200 mg). Following, the batch was cooled to 20-25 °C and agitated for 2 hours. The batch was filtered and the wet cake was washed with cold 2-methyl-2-butanol (43.2 mL, 2 vol). The batch was dried under reduced pressure to obtain TDAPP as a white solid. A sample was removed to monitor the drying by GC. The batch is deemed dry when the amount of 2-methyl-2-butanol is < 5,000 ppm. |