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Chemical Structure| 60694-99-7 Chemical Structure| 60694-99-7

Structure of 60694-99-7

Chemical Structure| 60694-99-7

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Product Details of [ 60694-99-7 ]

CAS No. :60694-99-7
Formula : C15H11NO
M.W : 221.25
SMILES Code : O=C(C1=CC=C(C#N)C=C1)CC2=CC=CC=C2
MDL No. :MFCD02260675

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Application In Synthesis of [ 60694-99-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 60694-99-7 ]

[ 60694-99-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 347-84-2 ]
  • [ 143-33-9 ]
  • [ 60694-99-7 ]
  • 2
  • [ 178686-24-3 ]
  • [ 60694-99-7 ]
  • [ 57-13-6 ]
  • [ 1283117-75-8 ]
YieldReaction ConditionsOperation in experiment
40% With hydrogenchloride; In ethanol; water; for 48.0h;Reflux; [00210] A mixture of 4-(2-phenylacetyl)benzonitrile (Intermediate 30) (50 mg, 0.23 mmol), 1,2-diphenylethanone (43 mg, 0.21 mmol), urea (41 mg, 0.68 mmol), andconcentrated HCl solution (0.02 mL, 0.21 mmol) in EtOH (5 mL) was heated at reflux for 48 h. The mixture was evaporated in vacuo, and the residue was purified by preparative HPLC to give Compound 63 (22.27 mg, yield 40%). 1H NMR (CD3OD 400 MHz): delta 7 '.62-7 '.59 (m, 3H), 7.42 (d, J = 8.0 Hz, 2H), 7.13-7.10 (m, 4H), 6.92-6.90 (m, 2H), 5.41 (s, 1H), 4.10-4.00 (m, 2H), 1.40 (t, J = 7.2 Hz, 3H); MS (ESI): m/z 457.0 [M+l]+.
 

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