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Chemical Structure| 5957-89-1 Chemical Structure| 5957-89-1

Structure of 5957-89-1

Chemical Structure| 5957-89-1

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Product Details of [ 5957-89-1 ]

CAS No. :5957-89-1
Formula : C12H11NO
M.W : 185.22
SMILES Code : COC1=CC=CC=C1C2=NC=CC=C2
MDL No. :MFCD06801886

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Application In Synthesis of [ 5957-89-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5957-89-1 ]

[ 5957-89-1 ] Synthesis Path-Downstream   1~3

  • 2
  • [ 33421-36-2 ]
  • [ 74-88-4 ]
  • [ 5957-89-1 ]
YieldReaction ConditionsOperation in experiment
The intermediate (1mmol,0.172g) was added to a slurry of K2CO3 (4mmol,0.552g) in DMF and stirred for 1h at rt before MeI (1.2mmol,0.118g) was a dded and stirred for 1h at rt. The reaction mixture was quenched with water, extracted with ethyl acetate, dried over MgSO4 and the solvent removed to give the title compound as a white solid (52%yieldovertwosteps). 1H NMR (300MHz,CDCl3) 8.70 (ddd,J=4.9,1.8,0.9Hz,1H), 7.87-7.74 (m,2H),7.68 (td,J=7.7,1.9Hz,1H),7.37(ddd,J=8.3,7.4,1.8Hz,1H),7.19(ddd,J=7.4,4.9,1.2Hz,1H),7.08(td,J=7.5,1.1Hz,1H),6.99(d,J=9.0Hz,1H),3.84(s,3H). Inaccordance with the literature.3
  • 3
  • [ 110-86-1 ]
  • [ 6971-45-5 ]
  • [ 5957-89-1 ]
  • [ 5958-01-0 ]
 

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