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Chemical Structure| 571-60-8 Chemical Structure| 571-60-8

Structure of 1,4-Dihydroxynaphthalene
CAS No.: 571-60-8

Chemical Structure| 571-60-8

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Product Details of [ 571-60-8 ]

CAS No. :571-60-8
Formula : C10H8O2
M.W : 160.17
SMILES Code : OC1=C2C=CC=CC2=C(O)C=C1
MDL No. :MFCD00003977
InChI Key :PCILLCXFKWDRMK-UHFFFAOYSA-N
Pubchem ID :11305

Safety of [ 571-60-8 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H315-H318
Precautionary Statements:P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P310-P501
Class:8
UN#:1759
Packing Group:

Application In Synthesis of [ 571-60-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 571-60-8 ]

[ 571-60-8 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 1122-12-9 ]
  • [ 571-60-8 ]
  • [ 99562-95-5 ]
  • 2
  • [ 293307-92-3 ]
  • [ 571-60-8 ]
  • [ 100570-24-9 ]
  • 3
  • [ 571-60-8 ]
  • [ 37688-96-3 ]
  • [ 1356382-69-8 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In N,N-dimethyl-formamide; at 140℃; for 12h;Inert atmosphere; General procedure: Hydroquinone or 1,4-dihydroxynaphthalene (5.0 mmol) and the corresponding dibromide (5.0 mmol) in dehydrated DMF (30 mL) were added dropwise over 12 h to a suspension of K2CO3 (12.5 mmol) in dehydrated DMF (50 mL) at 140 C. The reaction mixture was cooled to rt and filtered with Celite. The filtrate was treated with saturated NH4Cl aqueous solution and extracted with ethyl acetate. The organic layer was washed with water and brine. The extract was dried over Na2SO4 and evaporated under reduced pressure. The residue was filtered through a short plug of silica gel with dichloromethane and the filtrate was evaporated under reduced pressure. The crude products were purified by flash column chromatography (hexane/AcOEt=30/1∼20/1) and GPC (1,2-dichloroethane) to give dioxaparacyclophanes 1.
 

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