Home Cart Sign in  
Chemical Structure| 570416-08-9 Chemical Structure| 570416-08-9

Structure of 570416-08-9

Chemical Structure| 570416-08-9

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 570416-08-9 ]

CAS No. :570416-08-9
Formula : C10H13ClN4O2S
M.W : 288.75
SMILES Code : O=S(C1=C(Cl)N=C2C=CC(CCCC)=NN21)(N)=O

Safety of [ 570416-08-9 ]

Application In Synthesis of [ 570416-08-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 570416-08-9 ]

[ 570416-08-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 570416-08-9 ]
  • [ 2591-76-6 ]
  • [ 570416-09-0 ]
YieldReaction ConditionsOperation in experiment
59.6% N,N-Diisobutylformamide (5.44 g, 34.5 mmol) was dissolved in chloroform (25.0 mL) and cooled in an ice-sodium chloride bath, and phosphorus oxychloride (3.22 mL, 34.5 mmol) was added dropwise thereto at -2C or less. After the mixture was stirred at -2C or less for 30 minutes, 2,6-dichloroimidazo[1,2-b]pyridazin-3-ylsulfonamide (6.15 g, 23.0 mmol) was added thereto. After the mixture was stirred at -10C for 10 minutes, triethylamine (19.3 mL, 138 mmol) was added dropwise over 20 minutes to the solution at 5C or less. The mixture was stirred for 1 hour at 0C or less and for 1 hour at room temperature, then poured into an aqueous saturated sodium bicarbonate and extracted 5 times with chloroform. The extracts were combined, dehydrated over anhydrous magnesium sulfate and concentrated under reduced pressure. The residues were purified by silica gel column chromatography (ethyl acetate : hexane = 1 : 1) to give the title compound as pale yellow crystals. The yield was 5.58 g (59.6%). mp 151.0-154.0C1H NMR(CDCl3, δ): 0.76(6H, d, J=6.7 Hz), 0.97 (6H, d, J=6.7 Hz), 1.90-2.10(2H, m), 3.23(2H, d, J=7.6 Hz), 3.28(2H, d, J=7.7 Hz), 7.26(1H, d, J=9.5 Hz), 7.90(1H, d, J=9.5 Hz), 8.51(1H, s). IR(Nujol, cm-1): 1615, 1456, 1324, 1311, 1146, 910, 858, 654.
 

Historical Records

Technical Information

Categories